2020
DOI: 10.1148/radiol.2020200678
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Use of MRI for Personalized Treatment of More Aggressive Tumors

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“…Baricitinib and Ruxolitinib are potent and selective JAK inhibitors approved for indications such as rheumatoid arthritis and myelofibrosis [114] , which are currently reused for the treatment of SARS-CoV-2 infected patients. Studies have confirmed the safety and effectiveness of these drugs in reducing cytokine levels in the treatment of COVID-19 as antiviral drugs [115] , [116] , [117] . In addition, Baricitinib has the effect of reducing the endocytosis of the SARS-CoV-2 [118] .…”
Section: Drugs Targeting Sars-cov-2-induced Inflammation In Host Cellsmentioning
confidence: 88%
“…Baricitinib and Ruxolitinib are potent and selective JAK inhibitors approved for indications such as rheumatoid arthritis and myelofibrosis [114] , which are currently reused for the treatment of SARS-CoV-2 infected patients. Studies have confirmed the safety and effectiveness of these drugs in reducing cytokine levels in the treatment of COVID-19 as antiviral drugs [115] , [116] , [117] . In addition, Baricitinib has the effect of reducing the endocytosis of the SARS-CoV-2 [118] .…”
Section: Drugs Targeting Sars-cov-2-induced Inflammation In Host Cellsmentioning
confidence: 88%