Blood Cell - An Overview of Studies in Hematology 2012
DOI: 10.5772/50382
|View full text |Cite
|
Sign up to set email alerts
|

Use of Microfluidic Technology for Cell Separation

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
4
0

Year Published

2016
2016
2024
2024

Publication Types

Select...
3
2
1

Relationship

0
6

Authors

Journals

citations
Cited by 6 publications
(4 citation statements)
references
References 83 publications
(74 reference statements)
0
4
0
Order By: Relevance
“…Microfluidic systems can integrate different kinds of sorting methods based on the physical parameters of cells, providing a perfect interface for the manipulation of single cells and access forces in a variety of ways and allowing a fully autonomous measurement of physical parameters [58]. Particularly, cell separation techniques have been developed for cell concentration purposes (removal of plasma and increase of the cell concentration, mainly haematocrit increase); plasma enrichment (removal of cells from plasma and cells dilution); blood fractioning (separation of blood into different components); cell sorting (separation of cells by type); and cell removal (specific cell sorting that removes only some specific cells), that can work as cell isolation or removal of pathogenics [59].…”
Section: Microfluidic Cell Separation and Sorting Techniquesmentioning
confidence: 99%
See 1 more Smart Citation
“…Microfluidic systems can integrate different kinds of sorting methods based on the physical parameters of cells, providing a perfect interface for the manipulation of single cells and access forces in a variety of ways and allowing a fully autonomous measurement of physical parameters [58]. Particularly, cell separation techniques have been developed for cell concentration purposes (removal of plasma and increase of the cell concentration, mainly haematocrit increase); plasma enrichment (removal of cells from plasma and cells dilution); blood fractioning (separation of blood into different components); cell sorting (separation of cells by type); and cell removal (specific cell sorting that removes only some specific cells), that can work as cell isolation or removal of pathogenics [59].…”
Section: Microfluidic Cell Separation and Sorting Techniquesmentioning
confidence: 99%
“…Apart from these, there are other methods such as paper-based [60,61] and CD based [62,63] methods to separate mainly the plasma from blood [64]. Active technologies, based on microelectromechanical systems, improve the control of fluids using mobile parts or external mechanical forces, and can be based on dielectrophoresis, magnetophoresis, acoustophoresis and optical tweezers mechanisms [58,64]. Passive technologies for controlling fluids do not include external forces or mobile parts, and their control is promoted by diffusion as a function of the channel geometry [64,65,66,67,68,69,70], or intrinsic hydrodynamic forces, such as punch flow fraction, deterministic lateral displacement, inertial forces and intrinsic physical property of the cells [69,70,71,72,73,74], including sieving, which uses the size of micropores, microweirs, membranes and the gap between micropillars arrays for the separation of cells [26,69,70,71,72,73,74,75,76,77,78].…”
Section: Microfluidic Cell Separation and Sorting Techniquesmentioning
confidence: 99%
“…To move beyond proof of concept prototypes, these diverse applications of selective cell isolation require high accuracy and reproducibility [ 8 ]. Conventional cell isolation systems such as fluorescence-activated cell sorter (FACS), magnetic activated cell sorting (MACS) and centrifugation systems have demonstrated high robustness, accuracy and throughput and have high utility in industrial and lab settings.…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, all microfluidic cell sorting must furnish a gentle means of cell extraction and handling when performing on naturally live cells (Gross et al, 2015). Nevertheless, the other key challenges in cell sorting not only in all traditional methods but microfluidics are the discrimination of sorted cells in their sizes, densities, shapes, surface protein molecules (Mohamed, 2012), albeit these could be utilized for cell sorting, they are however bringing about a resolution interference of microdevice as well.…”
Section: Microfluidic Platforms For Single Cell Sorting and Entrapmentmentioning
confidence: 99%