2008
DOI: 10.1086/590356
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Use of Maximal Sterile Barrier Precautions and/or Antimicrobial-Coated Catheters to Reduce the Risk of Central Venous Catheter-Related Bloodstream Infection

Abstract: Central venous catheter-related bloodstream infection is clinically important because of its high mortality rate. This prospective study shows by multivariate analysis that the use of maximal sterile barrier precautions (odds ratio, 5.205 [95% confidence interval, 0.015-1.136]; P=.023) and the use of antimicrobial-coated catheters (odds ratio, 5.269 [95% confidence interval, 0.073-0.814]; P=.022) are independent factors associated with a lowered risk of acquiring a central venous catheter-related bloodstream i… Show more

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Cited by 29 publications
(15 citation statements)
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“…Therefore, to maintain a long-duration CP, we should consider factors such as expected prolonged neutropenia or age and the need for more careful nursing, especially for needling. Further study is warranted for preventive strategies such as skin antisepsis, maximum sterile barriers, use of antimicrobial catheters, and antimicrobial catheter lock solutions (16, 17). …”
Section: Discussionmentioning
confidence: 99%
“…Therefore, to maintain a long-duration CP, we should consider factors such as expected prolonged neutropenia or age and the need for more careful nursing, especially for needling. Further study is warranted for preventive strategies such as skin antisepsis, maximum sterile barriers, use of antimicrobial catheters, and antimicrobial catheter lock solutions (16, 17). …”
Section: Discussionmentioning
confidence: 99%
“…Use of maximal sterile barrier precautions during CVC insertion has been shown to reduce the incidence of CLABSIs compared to standard precautions. 26,79,[82][83][84] Third, catheters containing antimicrobial agents may be considered for hospital units with higher CLABSI rates than institutional goals, despite a comprehensive preventive strategy, and may be considered in specific patient populations at high risk of severe complications from a CLABSI. 11,69,80 Finally, providers should use a standardized procedure set-up when inserting CVCs to reduce the risk of CLABSIs.…”
Section: Rationalementioning
confidence: 99%
“…6 In addition, the relative risk of CRBSI in ICU2 was 0 after interventions, and the infection rates sustained 0 per 1000 catheter-days for 6 months in ICU2. We believe our modified standard procedure of CVC implantation could reduce the rates of CRBSI.…”
Section: Discussionmentioning
confidence: 96%
“…6 In addition, several large-scale studies support the observation that evidence-based interventions can reduce the rate of CRBSI. 1,7,8 The strategies for prevention of CRBSI include hand washing, using full-barrier precautions, cleaning the skin with chlorhexidine, catheter site selection (avoiding the femoral site), and removing unnecessary catheters.…”
Section: Introductionmentioning
confidence: 90%