Use of low frequency ultrasound for water treatment: Data on azithromycin removal

Muñoz-Calderón, Adrián; Zúñiga-Benítez, Henry; Valencia, Sergio; Rubio-Clemente, Ainhoa; Upegui, Sergio A; Peñuela, Gustavo A.

doi:10.1016/j.dib.2020.105947

Cited by 8 publications

(7 citation statements)

References 10 publications

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“…As shown in the previous section, in ultrasound technology, HO • is generated during cavitation according to Eq. 15 (Muñoz-Calderón et al 2020 ) in the range of 20 kHz to 10 MHz, and increased reaction time results in the production of HO • but increases energy consumption. …”

Section: Advanced Oxidation Processmentioning

confidence: 99%

SARS-CoV-2 pharmaceutical drugs: a critical review on the environmental impacts, chemical characteristics, and behavior of advanced oxidation processes in water

Castañeda-Juárez

Linares-Hernández

Martínez-Miranda

et al. 2022

Environ Sci Pollut Res

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This review summarizes research data on the pharmaceutical drugs used to treat the novel SARS-CoV-2 virus, their characteristics, environmental impacts, and the advanced oxidation processes (AOP) applied to remove them. A literature survey was conducted using the electronic databases Science Direct, Scopus, Taylor & Francis, Google Scholar, PubMed, and Springer. This complete research includes and discusses relevant studies that involve the introduction, pharmaceutical drugs used in the SARS-CoV-2 pandemic: chemical characteristics and environmental impact, advanced oxidation process (AOP), future trends and discussion, and conclusions. The results show a full approach in the versatility of AOPs as a promising solution to minimize the environmental impact associated with these compounds by the fact that they offer different ways for hydroxyl radical production. Moreover, this article focuses on introducing the fundamentals of each AOP, the main parameters involved, and the concomitance with other sources and modifications over the years. Photocatalysis, sonochemical technologies, electro-oxidation, photolysis, Fenton reaction, ozone, and sulfate radical AOP have been used to mineralize SARS-CoV-2 pharmaceutical compounds, and the efficiencies are greater than 65%. According to the results, photocatalysis is the main technology currently applied to remove these pharmaceuticals. This process has garnered attention because solar energy can be directly utilized; however, low photocatalytic efficiencies and high costs in large-scale practical applications limit its use. Furthermore, pharmaceuticals in the environment are diverse and complex. Finally, the review also provides ideas for further research needs and major concerns. Graphical abstract

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Section: Advanced Oxidation Processmentioning

confidence: 99%

SARS-CoV-2 pharmaceutical drugs: a critical review on the environmental impacts, chemical characteristics, and behavior of advanced oxidation processes in water

Castañeda-Juárez

Linares-Hernández

Martínez-Miranda

et al. 2022

Environ Sci Pollut Res

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“…The drug is a potential contaminant in aquatic systems that needs to be removed using the established economic and efficient method . There are several factors affecting the removal efficiency of the drug from contaminated water such as (a) the components (water and oil phases) of the nanoemulsion, (b) the physicochemical properties (viscosity, globular size, ferrous ions, hydrogen peroxide, and refractive index) of the nanoemulsion, (c) the degree of polluted water, (d) method efficiency, and (e) other factors (pH, UV frequency, reducing agent, microbial inhibition by antibiotics). − From the literature, it was concluded that the percent removal efficiency (%RE) of macrolides was comparatively lower than that of fluoroquinolones and the %RE values of ERN were 74 and 79% in wastewater treatment plants in Beijing and the United Kingdom (and Australia), respectively. , The drug can be estimated using previously reported methods based on the physicochemical nature of the drug. , The selection of excipients was based on various factors such as (a) the solubility of the drug, (b) the hydrophilic–lipophilic balance (HLB) value of the excipient, (c) medium-chain triglycerides capable of self-emulsification after dispersion into water, (d) capability of forming an emulsion through self-emulsification into water and subsequent adsorption of the lipophilic drug, (e) safety and biocompatibility, and (f) cost-effectiveness and ease of access. Labrafil M 1944 CS (LabM) consists chemically of mono-, di-, and triglycerides and PEG-6 (MW 300) mono- and diesters of oleic acid (C18:1) (source: Gattefossé leaflet).…”

Section: Introductionmentioning

confidence: 99%

“…Various conventional methods (physical, chemical, and microbial) have been exploited to remove macrolide contaminants from wastewater obtained from different water resources. , These conventional methods are the least efficient (unable to remove contaminants completely from water), hectic, and costly; have a high probability of microbial growth; and are difficult to scale up for bulk cleaning . Moreover, photocatalytic degradation, Fenton reaction, UV light application, ultrasound (low frequency ultrasound ∼40 kHz), and adsorption (activated carbon) based methods are commonly used techniques for remove trace amounts of macrolides present in aquatic systems despite several limitations. − Recently, we reported green nanoemulsions as nanocarriers for removing few macrolides and anti-tubercular pharmaceuticals (clarithromycin, azithromycin, and rifampicin) contaminating aqueous solutions. − These nanoemulsions are isotropic, and thermodynamically stable, composed of water, lipid, surfactant and co-surfactant. ERN is a poorly water-soluble (0.15 mg/mL) drug as evidenced by its log P value (2.6–3.06).…”

Section: Introductionmentioning

confidence: 99%

Green Nanoemulsion Water/Ethanol/Transcutol/LabM-Based Treatment of Pharmaceutical Antibiotic Erythromycin-Contaminated Aqueous Bulk Solution

et al. 2022

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Contaminated wastewater released from hospital, domestic, and industrial sources is a major challenge to aquatic animals and human health. In this study, we addressed removal of erythromycin (ERN) from contaminated water employing water/ethanol/Transcutol/Labrafil M 1944 CS (LabM) green nanoemulsions as a nanocarrier system. ERN is a major antibiotic contaminant harming aquatic and human lives. Green nanoemulsions were prepared and evaluated for size, size distribution (measuring polydispersity index), stability, zeta potential, refractive index, and viscosity. Transmission electron microscopy (TEM) was used to visualize morphological behavior. The treated-water was analyzed for ERN by the spectroscopy, scanning electron microscopy–energy-dispersive X-ray analysis mode (SEM–EDX), and inductively coupled plasma–optical emission spectroscopy (ICP–OES) techniques. We studied factors (composition, size, viscosity, and time of exposure) affecting removal efficiency (%RE). The obtained green nanoemulsions (ENE1–ENE5) were stable and clear (<180 nm). ENE5 had the smallest size (58 nm), a low polydispersity index value (0.19), optimal viscosity (∼121.7 cP), and a high negative zeta potential value (−25.4 mV). A high %RE value (98.8%) was achieved with a reduced size, a high water amount, a low Capryol 90 content, and optimal viscosity as evidenced by the obtained results. Moreover, contact time had insignificant effect on %RE. UV–vis spectroscopy, SEM–EDX, and ICP–OES confirmed the absence of ERN from the treated water. Conclusively, ERN can easily be removed from polluted water employing green nanoemulsions prepared from the optimized excipients, and evaluated characteristics.

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“…Very recently, low frequency ultrasound (40 kHZ) with or without hydrogen peroxide in aqueous solution was used to remove AZM. Authors studied the effect of solution pH (3-9), Fe ion, and UV light for the removal of AZM from aqueous solution using ultrasound (Muñoz-Calderón, et al 2020). The test was conducted at laboratory using an aqueous solution (1 mg/L) for 1 h in a reaction volume of 300 mL.…”

Section: Introductionmentioning

confidence: 99%

“…The removal e ciency was greatly in uenced with the external operational parameters such as pH, ultrasound, presence of ferrous ion, hydrogen peroxide and UV light. However, the achieved %RE was approximately 50 % only (Muñoz-Calderón, et al 2020). Furthermore, macrolides (erythromycin, azithromycin and clarithromyci) removal e ciencies were relatively lower as compared to uoroquinolones (cipro oxacin, o oxacin and nor oxacin) from the in uent of sewage wastewater collected from different countries (Ghosh et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Removal of azithromycin from aqueous bulk solution using water/ethanol/transcutol/capryol-90 green nanoemulsion

Hussain

Alshehri

Altamimi

et al. 2021

Preprint

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The present work aimed to remove azithromycin (AZM) from contaminated aqueous system using a water/ethanol/transcutol/capryol-90 green nanoemulsion. The drug is identified as potential pharmaceutical drug for detrimental effect on flora and fauna of aquatic lives and human health. Green nanoemulsions were tailored and characterized for thermodynamic stability, globular size, polydispersity index (PDI), zeta potential, viscosity, refractive index (RI), and morphological assessment using transmission electron microscopy (TEM). Moreover, nanoemulsions were investigated for percent removal efficiency and factors affecting the %RE. The results obtained from in vitro characterization parameters suggested that the developed green nanoemulsions (ANE1-ANE5) were stable, and possessing globular size ˂ 200 nm. ANE5 exhibited the lowest value of globular size (49 nm), low PDI (0.17), minimum viscosity (~ 93 cP), and optimum zeta potential (-27.8 mV). The value of %RE depended upon the content of water and capryol-90 oil of the nanoemulsion. Furthermore, the value of %RE was found to be increased with increased content of water and decreased concentration of capryol-90 in the nanoemulsions. Similarly, % RE value was increased with decreased value of globular size and decreased viscosity of nanoemulsion. There was no impact of contact time on %RE results. Thus, the maximum %RE value (96.8%) was obtained by ANE5 from the aqueous solution after 20 min of contact time with ANE5. Thus, this method could be a promising approach to remove AZM from a contaminated water and suitable alternative to conventional methods.

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Use of low frequency ultrasound for water treatment: Data on azithromycin removal

Cited by 8 publications

References 10 publications

SARS-CoV-2 pharmaceutical drugs: a critical review on the environmental impacts, chemical characteristics, and behavior of advanced oxidation processes in water

SARS-CoV-2 pharmaceutical drugs: a critical review on the environmental impacts, chemical characteristics, and behavior of advanced oxidation processes in water

Green Nanoemulsion Water/Ethanol/Transcutol/LabM-Based Treatment of Pharmaceutical Antibiotic Erythromycin-Contaminated Aqueous Bulk Solution

Removal of azithromycin from aqueous bulk solution using water/ethanol/transcutol/capryol-90 green nanoemulsion

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