Use of Leishmania-Derived Extracellular Vesicles as a Vaccine Platform Against Emerging Viral Diseases
Susan Cai
Abstract:Extracellular vesicles (EVs) are small membrane-bound “vehicles” responsible for transporting biological materials from source cells to target cells. EVs are thus indirectly capable of inducing changes in the physiological state and behavior of target cells once their contents are successfully released or received. Both prokaryotic and eukaryotic species utilize EVs for a variety of purposes. For example, Leishmania, a protozoan parasite, has demonstrated the ability to secrete immunomodulatory EVs. Various st… Show more
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