Use of lasers and light‐based therapies for treatment of acne vulgaris

Mariwalla, Kavita; Rohrer, Thomas E.

doi:10.1002/lsm.20276

Cited by 62 publications

(57 citation statements)

References 52 publications

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“…Laser and light-based therapy potentially clear acne with improvements in acne scarring and skin texture. Nonetheless, these methods are costly and pain causing [77].…”

Section: Tetracyclinesmentioning

confidence: 99%

Therapeutic agents and herbs in topical application for acne treatment

Kanlayavattanakul

Lourith

2011

Intern J of Cosmetic Sci

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SynopsisAcne vulgaris suppresses an individual's self-confidence by causing distress with regard to physical appearance, which affects a significant number of individuals during puberty and is delineated by adolescence. Several treatments have been introduced to decrease the aesthetic and psychological problems caused by acne. The topical application of therapeutic agents has been found to be more feasible than hormonal treatment and laser therapy. The ingredients in topical acne treatments, particularly herbs and naturally derived compounds, have received considerable interest as they have fewer adverse effects than synthetic agents. Ré suméL'acné vulgaire touche à l'assurance d'un individu en causant une détresse face à son apparence physique. Elle affecte un nombre important d'individus pendant la puberté et est associée à l'adolescence. Plusieurs traitements ont été proposés pour diminuer les problèmes esthétiques et psychologiques causés par l'acné. L'application topique d'agents thérapeutiques a été estimée plus aisée qu'un traitement hormonal et une thérapie laser. Les ingrédients des traitements topiques de l'acné, particulièrement les plantes et les composés naturels dérivés ont suscité un intérêt considérable par leurs moindres effets indésirables que les ingrédients synthé-tiques.

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“…Laser and light-based therapy potentially clear acne with improvements in acne scarring and skin texture. Nonetheless, these methods are costly and pain causing [77].…”

Section: Tetracyclinesmentioning

confidence: 99%

Therapeutic agents and herbs in topical application for acne treatment

Kanlayavattanakul

Lourith

2011

Intern J of Cosmetic Sci

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“…Over the last several years, several light-based systems have been employed in the management of acne vulgaris: photodynamic therapy with aminolevulenic acid, blue light alone, pulsed dye laser, KTP laser, several infrared lasers, and radiofrequency devices [6]. These methods are believed to target either P. acnes, the sebaceous glands or both.…”

Section: Introductionmentioning

confidence: 99%

The 1,450‐nm diode laser reduces sebum production in facial skin: A possible mode of action of its effectiveness for the treatment of acne vulgaris

2007

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Background and Objectives: Over the last several years, several light-based systems have been employed for the treatment of acne vulgaris. The 1,450-nm diode laser has been shown to improve acne, and this has been suggested to be due to effects on sebaceous glands. However, an effect on sebum production has not been demonstrated. The objective of this study was to evaluate if the 1,450-nm diode laser indeed reduces sebum production. Study Design/Materials and Methods: Eight patients with a history of acne were recruited and treated with the 1,450-nm diode laser on the right side of the nose over a 6-week period, for a total of three treatments. Sebum production was quantified using the Sebutape method. Results: The number of sebum-producing follicles was reduced by 8.5 and 16.7% at weeks 4 and 6, respectively (P<0.05). A significant reduction in total collected sebum (À18%) was observed at week 6. Conclusion: This data suggests that the clinical effectiveness of the 1,450-nm diode laser may be based, at least in part, on its effects on sebaceous glands, with subsequent reduction in sebum production.

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“…In addition to visible wavelengths of light, radiofrequency has also been used to treat acne [22]. Recently, the most commonly used laser modalities for treating acne with electromagnetic radiation are the infrared lasers [23][24][25][26][27][28][29]. These devices were originally developed for dermal remodeling and applied to treatment of rhytides and acne scarring.…”

Section: Introductionmentioning

confidence: 99%

“…One of the most widely used wavelengths for this purpose is the relatively recently developed 1,450 nm diode laser incorporating cryogen spray cooling (Smoothbeam, Candela Corporation, Wayland, MA). Initial studies treating acne scarring with the 1,450 nm diode laser revealed the potential to treat acne, and subsequent studies proved it to be effective at reducing acne [25][26][27][28][29].…”

Section: Introductionmentioning

confidence: 99%

A pilot investigation comparing low‐energy, double pass 1,450 nm laser treatment of acne to conventional single‐pass, high‐energy treatment

Bernstein

2006

Lasers Surg Med

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Background and Objectives: Laser treatment using a 1,450 nm diode laser has been shown to improve acne and acne scarring. Its widespread adoption in younger populations has been significantly limited by discomfort. Study Design/Materials and Methods: Six subjects with active papular acne were treated in a pilot study to determine parameters for a split-face, double-pass, lowenergy protocol of 1,450 nm laser treatment. Sides of the face were randomized to receive single-pass, high-energy treatment (13-14 J/cm 2 ), or double-pass, low energy treatment (8-11 J/cm 2 ), for a total of four treatments delivered at monthly intervals. Acne counts and standardized, digital photograph were performed 2 months following the final treatment, and compared to pre-treatment counts and photographs. Results: Improvement was evaluated comparing pre-and post-treatment photos and averaged 2.5 for the highenergy, single-pass side and 2.3 for the low-energy, double-pass side, using a 0 (worse) to 4 (max improvement) scale. Acne counts were reduced 78% on the high-energy, single-pass side and 67% on the low-energy, double-pass side. Pain ratings on a 1 (min) to 10 (max) scale averaged 5.6 (range 1-9) for the high-energy, single-pass side and 1.3 (range 1-2) for the low-energy, double-pass side. Conclusions: Low-energy, double-pass 1,450 nm laser treatment effectively reduces acne counts 2 months posttreatment, and dramatically reduces the pain associated with treatment. The treatment parameters used in this study have eliminated the need for anesthetic cream in daily practice.

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Use of lasers and light‐based therapies for treatment of acne vulgaris

Cited by 62 publications

References 52 publications

Therapeutic agents and herbs in topical application for acne treatment

Therapeutic agents and herbs in topical application for acne treatment

The 1,450‐nm diode laser reduces sebum production in facial skin: A possible mode of action of its effectiveness for the treatment of acne vulgaris

A pilot investigation comparing low‐energy, double pass 1,450 nm laser treatment of acne to conventional single‐pass, high‐energy treatment

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