Use of laryngeal mask airway compared to endotracheal tube with positive-pressure ventilation in anesthetized swine

Fulkerson, Pamela J; Gustafson, Scott

doi:10.1111/j.1467-2995.2006.00329.x

Cited by 26 publications

(14 citation statements)

References 20 publications

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“…Many reports have also strongly recommended LMA use for airway management in pigs 3,6,7 because LMA is consistently easier to place 7,15 and even inexperienced anesthesiologists can reliably secure the airway during spontaneous breathing in pigs. 6 According to Fulkerson and associates, LMA was successfully used with mechanical ventilation in 40-to 50-kg swine for 1 hour, resulting in faster and technically easier maintenance of airways with LMA versus ETT.…”

Section: Discussionmentioning

confidence: 99%

“…6 According to Fulkerson and associates, LMA was successfully used with mechanical ventilation in 40-to 50-kg swine for 1 hour, resulting in faster and technically easier maintenance of airways with LMA versus ETT. 3 Wemyss-Holden and associates reported that most swine undergoing general anesthesia do not require endotracheal intubation with specific indications and that LMA use results in the maintenance of spontaneous breathing for up to 6 hours without complications. 7 However, there are some limitations to the use of prolonged mechanical ventilation in pigs.…”

Section: Discussionmentioning

confidence: 99%

“…2 Because of compatible size and the potential ready availability, pigs are being developed as xenogeneic organ donors for use in humans. 2 In addition, since the 18th century, when the usefulness of swine models in the field of experimental biomedicine was first reported, pigs have been used as a standard experimental model 3 3 Even when it is performed by experienced operators, endotracheal intubation in pigs is not always successful. 7 Therefore, considering the era of xenotransplantation, a safe swine protocol to prevent organ ischemia during the anesthesia induction period is needed.…”

Section: Introductionmentioning

confidence: 99%

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Huh

Lim²,

Kim³

et al. 2017

Exp Clin Transplant

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Objectives: Organ transplant in humans is an established therapy for a variety of end-stage organ diseases. However, due to organ shortages and lack of donors, the need for xenotransplant has gradually increased. Xenotransplantation has great potential to solve many of the problems facing organ transplantation. Pigs are being developed as xenogeneic organ donors for use in humans. In this study, we propose a novel and simple method for tracheal intubation in a swine model using neuromuscular blocking agents and laryngeal mask airway. Material and Methods: Eight Yorkshire pigs were used for the 2 separate experiments, which were conducted 1 week apart. In the first experiment, an anesthesiologist with no previous comparable experience performed endotracheal intubation of pigs. One week later, using the same pig, a second experiment was performed by an experienced anesthesiologist. Anesthesia was induced with intramuscular injection of a mixture of 1 mg/kg xylazine (Rompun, Bayer Korea Ltd., Seoul, Korea) and 7 mg/kg Zoletil (a mixture of tiletamine hydrochloride and zolazepam hydro chloride, Virbac Laboratory, Carros, France). The laryngeal mask was then placed, and 0.15 mg/kg vecuronium bromide was injected intravenously. Tracheal intubation was attempted after mask removal. The duration and number of intubation attempts were recorded, and the degree of intubation difficulty was scored. Results: In all cases, the laryngeal mask was easily inserted, and endotracheal intubation was successfully completed. Oxygen saturation did not fall below 95%, and there were no hypoxemia episodes.Degree of intubation difficulty and duration were not significantly different between the 2 anesthesiologists. Conclusions: Tracheal intubation in our swine model was successfully performed using neuromuscular blocking agents and laryngeal masks without resulting in hypoxemia, with even anesthesiologists who are unfamiliar with endotracheal intubation of pigs easily able to do so using our protocol. Therefore, our protocol will enable all investigators to perform successful tracheal intubation in swine models.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Untitled

Huh

Lim²,

Kim³

et al. 2017

Exp Clin Transplant

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“…The use of laryngeal mask airways (LMAs) has been reported in dogs, cats, rabbits, pigs, and primates [9][10][11][12][13]. However, because of large patient size variations and the relative ease in which most of these species are intubated, LMAs are not extensively used in veterinary anesthesia.…”

Section: Airway Devicesmentioning

confidence: 98%

Veterinary Anesthesia

Schroeder

Smith

2011

Advances in Anesthesia

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“…Although LMAs have shown marked success in clinical anesthesia, the management of difficult airways, and emergency treatment, these devices also have disadvantages. [1][2][3][4][5][6] For example, an LMA cannot prevent stomach contents from refluxing into the respiratory tract and may move during surgery, affecting normal ventilation. In addition, an LMA may allow air leakage into the gastrointestinal tract during positive pressure ventilation, resulting in serious gastrointestinal distension and corresponding complications.…”

mentioning

confidence: 99%

A Novel Modified Laryngeal Mask Airway Allowing Full Separation of the Digestive and Respiratory Tracts, Along With Double-Catheter Ventilation, Diagnosis, and Treatment

Jia

Wang

Liu

2014

International Surgery

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The aim of this study was to design a novel, modified, multifunctional, and safe laryngeal mask airway (LMA). We designed an LMA with an internal catheter extending beyond the tip of the cuff. The protruding end of the internal catheter was provided with a catheter cuff, the space between the internal and external catheters was ventilatory, and the inlet ends of the 2 catheters were provided with standard connectors. We found that this design prevented reflux or aspiration of gastric content into the airway, prevented LMA dislocation, allowed ventilation through both the internal and external catheters, and allowed endoscopic examination and treatment of the gastrointestinal and respiratory tracts through both the internal and external catheters. This design overcomes the drawbacks and extends the functions of previous LMAs, offering a new approach to the development of LMAs.

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Use of laryngeal mask airway compared to endotracheal tube with positive-pressure ventilation in anesthetized swine

Cited by 26 publications

References 20 publications

Untitled

Untitled

Veterinary Anesthesia

A Novel Modified Laryngeal Mask Airway Allowing Full Separation of the Digestive and Respiratory Tracts, Along With Double-Catheter Ventilation, Diagnosis, and Treatment

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