Use of invasive cardiopulmonary exercise testing to diagnose preload reserve failure in patients with liver disease
Carolyn G. Ahlers,
Priyesh Patel,
Kishan Parikh
et al.
Abstract:In this case series, we describe the use of invasive cardiopulmonary exercise testing (iCPET) to diagnose heart failure due to preload reserve failure in two patients with progressive dyspnoea. We demonstrate that underlying liver disease contributes to preload reserve failure as a cause of exertional dysfunction. In liver diseases such as non‐alcoholic fatty liver disease (NAFLD), fibrotic changes to the sinusoidal liver architecture occur leading to an increased transhepatic sinusoidal pressure gradient. Eve… Show more
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