Use of intranasal esketamine in the treatment of treatment-resistant depression: A case report
Stefan Jerotić,
Joko Poleksić,
Maja Ivković
et al.
Abstract:Introduction: Treatment-resistant depression (TRD) refers to a depressive episode that has not responded to treatment with two antidepressants. Pharmacological strategies for treating TRD involve a complex process, which includes several options for the use of different psychopharmaceuticals, fundamentally consisting of: (1) substituting/optimizing the dose of antidepressants, or (2) augmenting antidepressant therapy. Within the augmentation strategy, NMDA antagonists, including intranasal esketamine, play a s… Show more
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