Use of hollow fiber liquid phase microextraction and HPLC for extraction and determination of apigenin in human urine after consumption of Satureja sahendica Bornm.

Hadjmohammadi, Mohammad Reza; Soltani, Mona; Sharifi, Vahid

doi:10.1016/j.jchromb.2012.05.022

Cited by 19 publications

(6 citation statements)

References 20 publications

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“…Although these effects have been discussed and there are some contradictory results, some experiments have mentioned that the addition of salt has a negative effect on extraction recovery as interaction between the analyte and salt leads to a decrease in diffusion rate of the analyte from the donor phase into the membrane organic solvent [29,30,42]. The effect of salt addition on the extraction efficiency of HA and MA were evaluated using solution containing 0–1.5 mol·L −1 of sodium chloride.…”

Section: Resultsmentioning

confidence: 99%

Hollow Fiber Supported Liquid Membrane Extraction Combined with HPLC-UV for Simultaneous Preconcentration and Determination of Urinary Hippuric Acid and Mandelic Acid

et al. 2017

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This work describes a new extraction method with hollow-fiber liquid-phase microextraction based on facilitated pH gradient transport for analyzing hippuric acid and mandelic acid in aqueous samples. The factors affecting the metabolites extraction were optimized as follows: the volume of sample solution was 10 mL with pH 2 containing 0.5 mol·L−1 sodium chloride, liquid membrane containing 1-octanol with 20% (w/v) tributyl phosphate as the carrier, the time of extraction was 150 min, and stirring rate was 500 rpm. The organic phase immobilized in the pores of a hollow fiber was back-extracted into 24 µL of a solution containing sodium carbonate with pH 11, which was placed inside the lumen of the fiber. Under optimized conditions, the high enrichment factors of 172 and 195 folds, detection limit of 0.007 and 0.009 µg·mL−1 were obtained. The relative standard deviation (RSD) (%) values for intra- and inter-day precisions were calculated at 2.5%–8.2% and 4.1%–10.7%, respectively. The proposed method was successfully applied to the analysis of these metabolites in real urine samples. The results indicated that hollow-fiber liquid-phase microextraction (HF-LPME) based on facilitated pH gradient transport can be used as a sensitive and effective method for the determination of mandelic acid and hippuric acid in urine specimens.

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Section: Resultsmentioning

confidence: 99%

Hollow Fiber Supported Liquid Membrane Extraction Combined with HPLC-UV for Simultaneous Preconcentration and Determination of Urinary Hippuric Acid and Mandelic Acid

et al. 2017

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“…For acidic analytes, the pH of the donor phase should be adjusted into the acidic region to suppress the ionization of analytes and keep them in their neutral form to be dissolved more effectively in organic solvent. The acceptor phase in this case should be an alkaline solution to guarantee the ionization of analytes and their extraction into the acceptor phase [ 6 ]. The situation for basic analytes is the reverse.…”

Section: Hflpementioning

confidence: 99%

“…In some cases, salt addition improves the extraction efficiency [ 21 , 22 ]. However, in some instances the extraction efficiency decreases by addition of salt [ 6 , 23 , 24 ]. These anomalous effects of salt addition could be explained using the following phenomena.…”

Section: Hflpementioning

confidence: 99%

Application of hollow fiber liquid phase microextraction and dispersive liquid–liquid microextraction techniques in analytical toxicology

Sharifi

Abbasi

Nosrati

2016

Journal of Food and Drug Analysis

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117

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The recent developments in hollow fiber liquid phase microextraction and dispersive liquid-liquid microextraction are reviewed. Applications of these newly emerging developments in extraction and preconcentration of a vast category of compounds including heavy metals, pesticides, pharmaceuticals and abused drugs in complex matrices (environmental and biological matrices) are reviewed and discussed. The new developments in these techniques including the use of solvents lighter than water, ionic liquids and supramolecular solvents are also considered. Applications of these new solvents reduce the use of toxic solvents and eliminate the centrifugation step, which reduces the extraction time.

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“…HFLPME coupled with high performance liquid chromatography (HFLPME with HPLC) has been used for the simultaneous preconcentration and quantification of trace amounts of active ingredients, such as magnolol and honokiol, [11] phenylpropionic acids, [12] ephedrine and pseudoephedrine, [13] valerenic acid, [14] flavonoids [15] in TCM samples, chlorogenic acid and its metabolites, [16] aristolochic acid, [17] apigenin, [18] magnoflorine, [19] and tramadol [20] in biological samples. The method has also been used in the study and determination of the binding properties of flavonoids, [21] alkaloids, [22] and furocoumarins.…”

Section: Introductionmentioning

confidence: 99%

STUDY ON ACTIVE INGREDIENTS OF LIGNANS FROM SCHISANDRA CHINENSIS BASED ON HOLLOW FIBER LIQUID PHASE MICROEXTRACTION

Chen

Liu

et al. 2014

Journal of Liquid Chromatography & Related Technologies

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& Hollow fiber liquid phase microextraction combined with high performance liquid chromatography (HFLPME with HPLC) is a simple, rapid, and sensitive method for the study on the pharmacokinetics of the active ingredients of lignans (i.e., schisandrol A, schisantherin A, schizandrin A, schizandrin B, and schizandrin C) from Schisandra chinensis after oral administration to rats. Several important HFLPME parameters, such as type of hollow fiber and extraction solvent, pH of sample phase, ionic strength, centrifugation speed, extraction time, and sample volume, were carefully investigated and optimized. Under optimal conditions, the enrichment factors for the five lignans in urine and plasma were within the ranges from 42.7 to 99.5 and 42.3 to 189.0, respectively. The linear ranges, limits of detection and quantification, precisions, and the mean recoveries and stabilities were satisfactory during the determination of five lignans in urine and plasma. The pharmacokinetics of five lignans was simultaneously studied in rats following intragastric administration of S. chinensis; the pharmacokinetic parameters were also estimated. The validated HFLPME with HPLC is suitable for the preconcentration and determination of trace amount of lignans in biological fluid. The method can also be used in research on the pharmacokinetics of active constituents in traditional Chinese medicines.

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Use of hollow fiber liquid phase microextraction and HPLC for extraction and determination of apigenin in human urine after consumption of Satureja sahendica Bornm.

Cited by 19 publications

References 20 publications

Hollow Fiber Supported Liquid Membrane Extraction Combined with HPLC-UV for Simultaneous Preconcentration and Determination of Urinary Hippuric Acid and Mandelic Acid

Hollow Fiber Supported Liquid Membrane Extraction Combined with HPLC-UV for Simultaneous Preconcentration and Determination of Urinary Hippuric Acid and Mandelic Acid

Application of hollow fiber liquid phase microextraction and dispersive liquid–liquid microextraction techniques in analytical toxicology

STUDY ON ACTIVE INGREDIENTS OF LIGNANS FROM SCHISANDRA CHINENSIS BASED ON HOLLOW FIBER LIQUID PHASE MICROEXTRACTION

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