Use of grafts in rotator cuff re-rupture

Jiménez-Martín, Antonio; Santos-Yubero, F.J.; Najarro-Cid, F.J.; Navarro-Martínez, Sergio; Zurera-Carmona, Manuel; Pérez-Hidalgo, Santiago

doi:10.1016/j.recote.2016.08.002

Cited by 2 publications

(3 citation statements)

References 59 publications

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“…Many biological and biosynthetic materials have been already studied as replacement of the abdominal wall 15 . Although routinely used in cardiothoracic and vascular surgery, neurosurgery, plastic surgery and orthopaedics [20][21][22][23][24][25][26][27]40,41 , equine pericardium has never been employed in bridging repair of the abdominal wall, perhaps because of described complications in other fields of employment likely related to host tissue reactions leading to degradation and leak 24 or fibrosis and shrinkage 41 .…”

Section: Discussionmentioning

confidence: 99%

“…The first experimental report about the use of the equine pericardium dates back to about forty years ago 20 . Since then, it has been used mainly in cardiothoracic and vascular surgery 21,22 , but also in neurosurgery 23,24 , orthopaedics 25 and plastic surgery 26,27 . A literature survey did not reveal studies devoted to the use of equine pericardium in the abdominal wall repair.…”

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confidence: 99%

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Bridging repair of the abdominal wall in a rat experimental model. Comparison between uncoated and polyethylene oxide-coated equine pericardium meshes

Pasculli

Gurrado

Luca

et al. 2020

Sci Rep

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Biological meshes improve the outcome of incisional hernia repairs in infected fields but often lead to recurrence after bridging techniques. Sixty male Wistar rats undergoing the excision of an abdominal wall portion and bridging mesh repair were randomised in two groups: Group A (n = 30) using the uncoated equine pericardium mesh; Group B (n = 30) using the polyethylene oxide (PEO)-coated one. No deaths were observed during treatment. Shrinkage was significantly less common in A than in B (3% vs 53%, P < 0.001). Adhesions were the most common complication and resulted significantly higher after 90 days in B than in A (90% vs 30%, P < 0.01). Microscopic examination revealed significantly (p < 0.05) higher mesh integrity, fibrosis and calcification in B compared to A. The enzymatic degradation, as assessed with Raman spectroscopy and enzyme stability test, affected A more than B. the peo-coated equine pericardium mesh showed higher resistance to biodegradation compared to the uncoated one. Understanding the changes of these prostheses in a surgical setting may help to optimize the peo-coating in designing new biomaterials for the bridging repair of the abdominal wall. Incisional hernia affects 10-20% of laparotomies and represents the most common long-term complication after abdominal surgery 1-3. Since their first description by Usher et al. in 1985 4 , synthetic prostheses significantly reduced recurrence rate after the first incisional hernia repair, from more than 20% to less than 10% 5,6. Nevertheless, they are commonly contraindicated in situations in which the exposure to any additional bacterial burden constitutes an excessive risk of surgical site infection 7,8. According to the Ventral Hernia Working Group (VHWG), incisional hernias which are at high risk of surgical site occurrences, because of comorbidities or contamination/infection of the operative field, should be treated using biological meshes; this should also be recommended in those cases in which the complete rectus closure is not possible and bridging technique is unavoidable 9. Although some controversies arose about the influence of technique in determining the surgical site occurrences 10 , and other authors designed and validated other scores 11,12 , VHWG recommendations appear to be still the most reliable guidelines available in the

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Bridging repair of the abdominal wall in a rat experimental model. Comparison between uncoated and polyethylene oxide-coated equine pericardium meshes

Pasculli

Gurrado

Luca

et al. 2020

Sci Rep

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“…Tendon augmentation with porcine SIS has been related to failure in clinical trials, 177‐179 with no improvement in healing and mechanical properties, which was associated to the inefficient decellularization and the consequent immune reaction, as reported in in vivo studies 180,181 . Crosslinked xenografts, such as equine pericardium, did not yield positive outcomes in clinical trials, 35,182 which can be attributed to crosslinking‐induced immune reactions. Porcine dermis xenografts (eg Conexa ® 183,184 ) on the other hand have shown positive results in tendon augmentation, 185‐187 possibly attributed to efficient decellularization and/or crosslinking protocols and selecting a tissue with appropriate composition and mechanical resilience.…”

Section: Xenografts In Clinical Indicationsmentioning

confidence: 97%

Decellularized xenografts in regenerative medicine: From processing to clinical application

Capella-Monsonís

Zeugolis

2021

Xenotransplantation

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Decellularized xenografts are an inherent component of regenerative medicine. Their preserved structure, mechanical integrity and biofunctional composition have well established them in reparative medicine for a diverse range of clinical indications. Nonetheless, their performance is highly influenced by their source (ie species, age, tissue) and processing (ie decellularization, crosslinking, sterilization and preservation), which govern their final characteristics and determine their success or failure for a specific clinical target. In this review, we provide an overview of the different sources and processing methods used in decellularized xenografts fabrication and discuss their effect on the clinical performance of commercially available decellularized xenografts.

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Use of grafts in rotator cuff re-rupture

Cited by 2 publications

References 59 publications

Bridging repair of the abdominal wall in a rat experimental model. Comparison between uncoated and polyethylene oxide-coated equine pericardium meshes

Bridging repair of the abdominal wall in a rat experimental model. Comparison between uncoated and polyethylene oxide-coated equine pericardium meshes

Decellularized xenografts in regenerative medicine: From processing to clinical application

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