Use of glycerolized human allografts as temporary (and permanent) cover in adults and children

Hussmann, J.; Russell, Robert C.; Kucan, John O.; Hebebrand, D.; Bradley, Timothy M.; Steinau, H. U.

doi:10.1016/0305-4179(94)90093-0

Cited by 25 publications

(7 citation statements)

References 23 publications

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“…The process of radiating the skin has multiple advantages, serving as a preservative as well as a sterilising adjuvant. Gamma‐irradiation coupled with extensive serological testing performed by skin banks insures safety (15–18). This, coupled with its simplistic application, handling and accessibility, yields a product that we have found very useful in the healing of lower extremity wounds.…”

Section: Gamma‐irradiated Skin Graftsmentioning

confidence: 99%

Gamma‐irradiated human skin allograft: a potential treatment modality for lower extremity ulcers

Rosales

Bruntz

Armstrong

2004

International Wound Journal

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Gamma-irradiated human skin allograft consists of epidermis and dermis. Unlike bioengineered tissues which require cold storage and timely use once received from the manufacturer, gamma-irradiated human skin allograft can be stored for as long as 24 months at room temperature. This modality is applied in a fashion similar to that of bioengineered skin grafts. In this article, we present case studies with concise reviews of the available evidence to discuss the potential use of gamma-irradiated human skin allograft on wounds in the lower extremity.

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Section: Gamma‐irradiated Skin Graftsmentioning

confidence: 99%

Gamma‐irradiated human skin allograft: a potential treatment modality for lower extremity ulcers

Rosales

Bruntz

Armstrong

2004

International Wound Journal

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“…The preservation of allografts can be performed by different techniques, such as freeze‐drying, 25 glutaraldehyde fixation, 26 or glycerolization. 27 Cryopreservation of homografts with glycerol is the most popular method of cadaver skin processing since freeze‐drying is too expensive and glutaraldehyde fixation is less efficient. 28 Moreover, skin preservation can reduce the risk of virus transmission from skin grafting, providing time to rid the donor skin of pathogens.…”

Section: Wound Coverage With Allogeneic Skinmentioning

confidence: 99%

“…Indeed, incubation of cadaver skin for several hours at 37°C in glycerol produces a significant virucidal and bactericidal effect. 27 In order to provide sufficient cadaver skin instantly accessible for burn patients, skin banks such as the Euro Skin Bank in Beverwijk, The Netherlands, have been developed over the years. 29 However, allogeneic skin banking has a significantly higher cost compared to xenogeneic skin banking and biological dressings.…”

Section: Wound Coverage With Allogeneic Skinmentioning

confidence: 99%

Modern Aspects of Wound Healing: An Update

Ruszczak

Schwartz

2000

Dermatologic Surgery

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Wound healing is an area of cutaneous medicine in which there have been many recent advances. Interest has focused on the development of an in vitro reconstructed skin, although neither the commercially available products nor the products currently described in experimental studies are able to fully substitute for natural living skin. The substitution of the main component of each wound, the connective tissue matrix, is an advance. Once dermis is reconstructed, the covering of the wound surface with both in vitro expanded epidermis and autologous split-skin transplants is significantly easier and has an improved chance of success. Epidermal stem cells may facilitate functionality of the superficial part of such a system. New experimental and clinical trials are currently under way.

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“…Sua indicação clínica principal é para a cobertura de queimaduras de espessura total pós escarectomia em pacientes que não possuam área doadora suficiente (grandes queimados). Ela também pode ser usada como um curativo biológico para a cobertura temporária de queimadura de espessura parcial, como as queimaduras por líquidos aquecidos, situação na qual permanece por 3 a 5 dias, estimulando assim a reepitelização da ferida 2,3 . Outra indicação importante é na cobertura de enxertos autógenos em malha, oferecendo melhor proteção da ferida com cobertura completa do tecido autógeno enxertado; são os enxertos ditos "em sanduíche" 4 .…”

Section: Introductionunclassified

An�lise da influ�ncia de uma equipe de capta��o de pele em um Banco de Tecidos- estudo transversal

Paggiaro

Conceição²,

Parra³

et al. 2019

Rev. Saude

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Introdu��o: Os aloenxertos cut�neos s�o considerados padr�o ouro para o tratamento de pacientes com extensas queimaduras. Objetivo: Avaliar o impacto de uma equipe de capta��o de pele no estoque de um Banco de Tecidos. M�todo: Foi realizado um estudo transversal, documental, avaliando os prontu�rios dos doadores de pele do Banco de Tecidos do ICHC no per�odo entre 2012 a abril de 2019. Avaliou-se o n�mero de doadores e a rentabilidade por m�dico. Resultados: Foram efetuadas 73 capta��es, com o maior n�mero (19) ocorrendo no ano de 2018, dois anos ap�s o retorno da equipe de capta��o. No ano de 2013, em que n�o havia uma equipe, houve o menor n�mero de procedimentos (3). Os m�dicos com maior n�mero de capta��es, conseguiam melhor rentabilidade de tecido. Conclus�o: A presen�a de uma equipe pr�pria e treinada aumenta o n�mero e a rentabilidade das capta��es, acarretando em aumento do estoque de tecido.

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Use of glycerolized human allografts as temporary (and permanent) cover in adults and children

Cited by 25 publications

References 23 publications

Gamma‐irradiated human skin allograft: a potential treatment modality for lower extremity ulcers

Gamma‐irradiated human skin allograft: a potential treatment modality for lower extremity ulcers

Modern Aspects of Wound Healing: An Update

An�lise da influ�ncia de uma equipe de capta��o de pele em um Banco de Tecidos- estudo transversal

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