Use of Fluorine-18 Fluoro-2-deoxy-D-glucose Positron Emission Tomography in Assessing the Process of Tuberculous Spondylitis

Schmitz, Alfred; Kälicke, T.; Willkomm, P.; Grünwald, Frank; Kandyba, J.; Schmitt, O.

doi:10.1097/00002517-200012000-00016

Cited by 38 publications

(18 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The foci of FDG uptake in lymph node region in our patients were consistent with recurrence of the primary cancer or lymphoma. In retrospective analysis, they were also consistent with tuberculosis dissemination to lymph nodes (16).…”

Section: F I G U R E 3 Co R O N a L ( A) A N D S A G I T T A L ( B supporting

confidence: 64%

Abnormal FDG Uptake on 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients with Cancer Diagnosis: Case Reports of Tuberculous Lymphadenitis

et al. 2009

View full text Add to dashboard Cite

show abstract

Section: F I G U R E 3 Co R O N a L ( A) A N D S A G I T T A L ( B supporting

confidence: 64%

Abnormal FDG Uptake on 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients with Cancer Diagnosis: Case Reports of Tuberculous Lymphadenitis

et al. 2009

View full text Add to dashboard Cite

show abstract

“…PET-CT is another metabolic imaging technique, based on the glucose-cellular consumption, with a high-contrast rate between lesion and background [32,35,38] (Fig. 10).…”

Section: Radionuclide Studiesmentioning

confidence: 99%

Imaging findings of Pott’s disease

Rivas-Garcia¹,

et al. 2012

View full text Add to dashboard Cite

Tuberculosis (TB) continues to be an important public health problem in developed countries especially in deprived socioeconomic groups, older people, immunocompromised patients, drug-therapy resistant cases and the immigrant population. The spine is the most frequent location of musculoskeletal TB. The wide range of clinical presentations results in difficulties and delays in diagnosis. Advanced disease mimics other infections and malignancy. The diagnosis of spinal infections relies on three main factors: clinical symptoms, imaging and bacteriological culture. Advanced imaging such as Magnetic Resonance Imaging (MRI), Multidetector Computed Tomography (MDCT) and Fluor18-Deoxiglucose Positron Emission Tomography combined with CT (F-18 FDG PET-CT) demonstrate lesion extent, serve as guide for biopsy with aspiration for culture, assist surgery planning and contribute to follow-up. Diagnosis of TB cannot be established solely on the basis of clinical tests or imaging findings and biopsy may be required. Differential diagnosis between tuberculous and pyogenic spondylitis is of clinical importance, but may be difficult on the basis of radiological findings alone. Findings not pathognomonic but favoring tuberculous etiology include: slow progression of lesions with late preservation of disk space, involvement of several contiguous segments, large intraosseous and paraspinal abscesses containing calcifications, and body collapse with kyphotic deformity. In this essay the highlights of TB imaging are reviewed through published literature. In addition, we review retrospectively the radiological findings of 48 patients with tuberculous spondylitis treated from 1993 to 2010. There were 23 male and 25 female patients with a mean age of 53 years.

show abstract

“…More rarely, an increased uptake of labelled leukocytes can be found in the site of vertebral infection that has been correlated to the duration of symptoms: less than 25% of patients who were symptomatic for more than 2 weeks showed presented such findings [22]. F-FDG PET [35][36][37][38][39][40][41], have shown high sensitivity but variable specificity (ranging from 35.8% to 87.9%), especially in cases in that require differentiating vertebral infection from benign pathologies or septic and aseptic SD in the early post-surgical phase [40][41][42][43][44][45].…”

Section: In-biotin Spect/ctmentioning

confidence: 99%