Use of Elemental Diet During the Adaptive Stage of Short Gut Syndrome

Small-Intestinal Changes Induced by an Elemental Diet (Vivonex) in Normal Rats

“…The effect of different types of oral nutrition, and in particular the influence of elemental diets, on smallbowel structure and function has not been fully investigated. Elemental diets have been shown to be beneficial during the adaptive phase of short-gut syndrome in man (Voitk, Echave, Brown & Gurd, 1973) and have been used for nutritional support in Crohn's disease (Goode, Hawkins, Feggetter & Johnstone, 1976) and in the management of cholerheic diarrhoea associated with Crohn's disease and ileal resection (Nelson, Carmichael & Russell, 1977). A diet containing hydrolysed casein promotes faster recovery of intestinal mucosa in irradiated mice than whole casein or Purina diets (Huggon, 1976).…”

Sixth annual Jonathan E. Rhoads lecture. Enteral Nutrition: Tube Feeding in Acute and Chronic Illness

“…Similarly, of other amino acids measured, 12 in the Johnston series decreased 29% and 18 in the Jain series decreased 25%. However, by 96 hr in both series, branched-chain amino acids concentrations were above control levels, phenylalanine and methionine had increased slightly while histidine, proline, glutamic acid, and glycine levels remained significantly low. Results for the two series, combined when two sets of amino acid concentrations were reported, are shown in Table VIII. We measured the plasma-free amino acid concentration of 25 amino acids including AABA in five nonseptic patients in the jejunostomy feeding series.…”

An Improved Technique for Needle Catheter Jejunostomy

“…[2][3][4][5][6][7] The administration of this preparation by the jejunal route requires carefully controlled, gradually increasing concentration of the solution to avoid symptoms of bloating and diarrhea.-' In addition, recent reports by Slesinger and Silk question the routine use of pure amino acid preparations for nutritional support.8*3 The use of a larger catheter jejunostomy offers a range of possibilities for nutritional support by this route. In addition to bedside prepared hand-mixed solutions, commercially prepared nutrients tailored to specific patient needs can be adminis¬ tered.…”