Use of Early Goal-Directed Therapy for Severe Sepsis and Septic Shock in a Community Hospital Lowers Resource Consumption and Cost.

Early goal-directed therapy in severe sepsis and septic shock: a contemporary review of the literature

“…The total cost benefit favored EGDT and costs saving projected at $3.5 million per year for the institution. Becker Joffe and Lidsky [61] showed that poor patient response to EGDT may lead to earlier end of life discussions such that nonsurvivors of a septic episode will undergo withdrawal of therapy sooner resulting in cost savings. In this manner EGDT was associated with a significant decrease in duration of mechanical ventilation (2.8 days, P ¼ 0.02), strong trends toward reduction in ICU and hospital resources, and cost savings.…”