2021
DOI: 10.4414/smw.2021.w30048
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Use of drugs to treat symptoms and acute conditions during pregnancy in outpatient care in Switzerland between 2014 and 2018: analysis of Swiss healthcare claims data

Abstract: BACKGROUND: Evidence on the use of drugs during pregnancy in Switzerland is lacking. OBJECTIVES: To evaluate utilisation of prescribed drugs during pregnancy in outpatient care in Switzerland, focusing on treatments for pain, infections, gastro-oesophageal reflux, nausea/vomiting, and constipation. METHODS: We conducted a descriptive study using the Swiss Helsana claims database (2014–2018). We established a cohort of pregnancies by identifying deliveries and estimating the date of the last menstrual period. W… Show more

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Cited by 13 publications
(10 citation statements)
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“…The most changed "chronic" medications reported by women were analgesics and antihistamines. The identification of these classes is, however, not surprising given that both classes are typically the most used ones during pregnancy and postpartum [32,33], which was also the case in our study population. Although asthma medications were not among the ten most used classes in our study, they were the fourth most changed class due to COVID-19.…”
Section: Main Findingssupporting
confidence: 56%
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“…The most changed "chronic" medications reported by women were analgesics and antihistamines. The identification of these classes is, however, not surprising given that both classes are typically the most used ones during pregnancy and postpartum [32,33], which was also the case in our study population. Although asthma medications were not among the ten most used classes in our study, they were the fourth most changed class due to COVID-19.…”
Section: Main Findingssupporting
confidence: 56%
“…However, similarly to the first wave (3%), the self-reported use of systemic antibiotics was less prevalent among pregnant women (2%) than in prepandemic reports. Indeed, 14% of Lupatelli et al's pregnant participants reported having used a systemic antibiotic [32], and at least 26% of women were prescribed an antibiotic at some point in pregnancy, according to a recently published Swiss claims database cohort [33]. Although our prevalence of systemic antibiotic use may be underestimated due to questioning only the three preceding months, the use/dispensing of systemic antibiotics was equally frequent in each pregnancy trimester in both studies [32,33].…”
Section: Main Findingsmentioning
confidence: 69%
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“…Specific groups of medicines for which HCPs want information were identified, including systemic anti-infectives and respiratory and alimentary tract medicines. These medicines are also regularly used in this population [ 30 , 31 , 32 , 33 , 34 , 35 ]. Moreover, women and HCPs expressed their interest in having access to information on herbal remedies.…”
Section: Discussionmentioning
confidence: 99%