Use of Diffusion Tensor Imaging to Examine Subacute White Matter Injury Progression in Moderate to Severe Traumatic Brain Injury

Greenberg, Gahl; Mikulis, David J.; Ng, Kester; DeSouza, Danielle D.; Green, Robin

doi:10.1016/j.apmr.2008.08.211

Cited by 68 publications

(49 citation statements)

References 37 publications

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“…Neuroimaging in the subacute and chronic phase of TBI has demonstrated hippocampal atrophy, white matter connectivity changes, and defined areas of encephalomalacia that may be resected for the treatment of epilepsy. 8,10,20 While there are no specific guidelines on repeat imaging in patients during the subacute or chronic phase of TBI, the present case emphasizes the fact that new or worsening symptoms remote from a TBI still warrant radiographic investigation.…”

Section: Discussionmentioning

confidence: 99%

Development of a de novo arteriovenous malformation after severe traumatic brain injury

Miller

Bass

Chern

2014

PED

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Arteriovenous malformations (AVMs) are typically considered congenital lesions, although there is growing evidence for de novo formation of these lesions as well. The authors present the case of an AVM in the same cerebral cortex that had been affected by a severe traumatic brain injury (TBI) more than 6 years earlier. To the best of the authors' knowledge, this is the first report attributing the formation of an AVM directly to TBI.

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Section: Discussionmentioning

confidence: 99%

Development of a de novo arteriovenous malformation after severe traumatic brain injury

Miller

Bass

Chern

2014

PED

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“…In the past year, serial studies of DTI in moderate to severe TBI have been published that demonstrated a longitudinal decrease in FA during the first year post-injury (31)(32)(33). An even more recent longitudinal 3T DTI tractography study of mild TBI showed that, compared to age, gender, and education matched controls, reduced FA can be detected in WM tracts of mild TBI patients by two weeks post-injury and that this reduced FA persists for at least one year after injury (34).…”

Section: Conventional Mri Techniquesmentioning

confidence: 99%

Common data elements in radiologic imaging of traumatic brain injury

Haacke,

Duhaime,

Gean

et al. 2010

Magnetic Resonance Imaging

165

166

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Traumatic brain injury (TBI) has a poorly understood pathology. Patients suffer from a variety of physical and cognitive effects that worsen as the type of trauma worsens. Some noninvasive insights into the pathophysiology of TBI are possible using magnetic resonance imaging (MRI), computed tomography (CT), and many other forms of imaging as well. A recent workshop was convened to evaluate the common data elements (CDEs) that cut across the imaging field and given the charge to review the contributions of the various imaging modalities to TBI and to prepare an overview of the various clinical manifestations of TBI and their interpretation. Technical details regarding state-of-the-art protocols for both MRI and CT are also presented with the hope of guiding current and future research efforts as to what is possible in the field. Stress was also placed on the potential to create a database of CDEs as a means to best record information from a given patient from the reading of the images.

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“…All studies, except 5, compared subjects with TBI with a control group. 17,18,24,83,85 Three of these exceptions used a longitudinal within-subjects design. 24,83,85 In all except 7 studies, control subjects were healthy individuals.…”

Section: Subjects With Tbimentioning

confidence: 99%

“…17,18,24,83,85 Three of these exceptions used a longitudinal within-subjects design. 24,83,85 In all except 7 studies, control subjects were healthy individuals. 28 that did not use healthy individuals as control subjects, 2 groups of subjects with TBI were compared (eg, with and without major depressive disorders 53 ).…”

Section: Subjects With Tbimentioning

confidence: 99%

A Decade of DTI in Traumatic Brain Injury: 10 Years and 100 Articles Later

Hulkower

Poliak

Rosenbaum

et al. 2013

AJNR Am J Neuroradiol

390

324

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SUMMARY:The past decade has seen an increase in the number of articles reporting the use of DTI to detect brain abnormalities in patients with traumatic brain injury. DTI is well-suited to the interrogation of white matter microstructure, the most important location of pathology in TBI. Additionally, studies in animal models have demonstrated the correlation of DTI findings and TBI pathology. One hundred articles met the inclusion criteria for this quantitative literature review. Despite significant variability in sample characteristics, technical aspects of imaging, and analysis approaches, the consensus is that DTI effectively differentiates patients with TBI and controls, regardless of the severity and timeframe following injury. Furthermore, many have established a relationship between DTI measures and TBI outcomes. However, the heterogeneity of specific outcome measures used limits interpretation of the literature. Similarly, few longitudinal studies have been performed, limiting inferences regarding the long-term predictive utility of DTI. Larger longitudinal studies, using standardized imaging, analysis approaches, and outcome measures will help realize the promise of DTI as a prognostic tool in the care of patients with TBI. ABBREVIATIONS:FA ϭ fractional anisotropy; GCS ϭ Glasgow Coma Scale; MD ϭ mean diffusivity; TAI ϭ traumatic axonal injury; TBI ϭ traumatic brain injury;

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Use of Diffusion Tensor Imaging to Examine Subacute White Matter Injury Progression in Moderate to Severe Traumatic Brain Injury

Cited by 68 publications

References 37 publications

Development of a de novo arteriovenous malformation after severe traumatic brain injury

Development of a de novo arteriovenous malformation after severe traumatic brain injury

Common data elements in radiologic imaging of traumatic brain injury

A Decade of DTI in Traumatic Brain Injury: 10 Years and 100 Articles Later

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