Use of Differential Reaction Rates to Analyze Mixtures of Organic Materials Containing the Same Functional Group-Application to Amides and Nitriles.

Analysis of multicomponent ester mixtures by dual temperature differential kinetics

“…Data for one of these mixtures indicate an average deviation (error) in concentrations of between 4 and 6%.…”

“…The present study, which involves the secondorder extrapolation approach, was initiated in an attempt to expand the limits of differential kinetic analysis by using temperature variation reactions.Kinetic methods for analysis of binary mixtures have been devised to treat a great number of systems. These have included such procedures as the single point method (/), originally applied to ester mixtures; first-order reaction method of proportional equations (2); and various functional group analyses by graphical logarithmic extrapolation (3,4). Individual criteria dictate the advantages to be gained by selection of one technique over the others.…”

Kinetic Aspects of Analytical Chemistry

“…Siggia and coworkers (71) also demonstrated the application of dialysis methods to the kinetic analysis of mixtures; two and three component mixtures of sugars and amino acids could be resolved by dialysis through thin films on the basis of their differing diffusion rates. Amides and nitriles were analyzed (70) with good accuracy by measuring the rate evolution of ammonia generated by the alkaline hydrolysis of their compounds. Spectrophotometric monitoring of reaction rates was used by Willeboordse and Critchfield (82) to analyze binary and ternary mixtures of alcohols undergoing reaction with phenylisocyanate and by Mark,Backes,and Pinkel (49) in the determination of sugar mixtures using 2,3,5-Triphenyl-2H-Tetrazolium chloride as a specific reagent.…”

Volumetric and Gravimetric Analytical Methods for Organic Compounds

“…Amides. The differential reaction rate method has been applied to the analysis of mixtures of amides (124)• Samples were heated in water-tetrahydrofuran containing NaOH and then subjected to a Kjeldahl-type distillation.…”