Use of dexmedetomidine infusion in anaesthesia for awake craniotomy

Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial † †Euroanaesthesia Congress, May 31, 2015, Berlin, Germany, and Canadian Anesthesiologists’ Society Annual Meeting, June 20, 2015, Ottawa, Canada. ‡ ‡This Article is accompanied by Editorial Aew113.

“…Subsequent studies evaluating the influence of dexmedetomidine on the ability to perform intraoperative neurologic testing showed inconsistent results. [34][35][36] One recent case report 37 and several case series of awake craniotomies for tumour resection advocate an anaesthetic approach based on scalp nerve blocks and dexmedetomidine with 38 or without airway manipulation. 39 40 Another study compared the combinations of dexmedetomidine and remifentanil to propofol and remifentanil during AC using an 'asleep-awake-asleep' technique involving general anaesthesia with orotracheal intubation.…”

Awake reduction of hangman's fracture: An era of dexmedetomidine

“…It is relatively more cardiostable compared to clonidine and it has a favourable effect on intracranial pressure. Its role is well established in awake craniotomies but its role in closed reduction of cervical spine is still unexplored [ 1 ]. We used this drug for closed reduction of Hangman's fracture because of unavailability of SSEP and MEP monitors.…”

Awake craniotomy anesthetic management using dexmedetomidine, propofol, and remifentanil

“…Kallapur and Bhosale 9 reported a case of tumor removal with awake craniotomy, using scalp block without 3-pin holder, with simultaneous infusion of DEX and PRO and oxygen delivery through a simple mask. They concluded that DEX is a useful adjuvant during awake craniotomy for tumor resection.…”