Use of dermoscopy in the diagnosis of sebaceoma

Coppola, Rosa; Carbotti, Mattia; Zanframundo, Salvatore; Rinati, Maria Verona; Graziano, Antonio; Panasiti, Vincenzo

doi:10.1016/j.jaad.2014.12.004

Cited by 10 publications

(8 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The yellowish structures are common dermoscopic features in sebaceous tumors, including sebaceous hyperplasia, sebaceoma and SC. According to previous studies, dermoscopic features of sebaceous hyperplasia include a crown of vessels with a radial arrangement surrounding a white‐yellowish polylobular center, whereas the dermoscopy of sebaceoma reveals homogeneous, translucent yellow‐pinkish areas, with peripheral arborizing vessels and sometimes central ulceration 14,17 . The present study showed that purplish globules, shiny white blotches and strands, and whitish‐pink area were significantly associated with SC.…”

Section: Discussionsupporting

confidence: 64%

“…According to previous studies, dermoscopic features of sebaceous hyperplasia include a crown of vessels with a radial arrangement surrounding a white-yellowish polylobular center, whereas the dermoscopy of sebaceoma reveals homogeneous, translucent yellow-pinkish areas, with peripheral arborizing vessels and sometimes central ulceration. 14,17 The present study showed that purplish globules, shiny white blotches and strands, and whitish-pink area were significantly associated with SC. The result indicated that intratumoral hemorrhage and stromal fibrosis were more common in cases of SC histopathologically.…”

Section: Discussionsupporting

confidence: 48%

See 1 more Smart Citation

Dermoscopic features and differential diagnosis of sebaceous carcinoma

Cheng

Kuo

2020

The Journal of Dermatology

View full text Add to dashboard Cite

Sebaceous carcinoma is a rare malignant skin neoplasm arising from sebaceous glands. Its clinical diagnosis is difficult and reports of dermoscopic findings have been limited. This study aims to analyze its dermoscopic features and differential diagnosis in dermoscopic examination. The study included patients diagnosed with histologically proven sebaceous carcinomas as well as diagnosed cases of sebaceous hyperplasia, sebaceoma, squamous cell carcinoma and basal cell carcinoma for comparison of dermoscopic findings. The dermoscopic criterion of presence of sebaceous carcinoma was scored only if the two evaluators reached a consensus. Fifteen cases of histologically diagnosed sebaceous carcinoma were included in our study. All cases were extraocular sebaceous carcinoma. A total of 60 (15 basal cell carcinomas, 15 squamous cell carcinomas, 15 sebaceous hyperplasias and 15 sebaceomas) cases were collected for comparing dermoscopic features with sebaceous carcinoma. In dermoscopic analysis of sebaceous carcinoma, the majority of tumors (66.67%) presented polymorphic vessel pattern. Other features included whitish-pink areas (80%), yellowish structures (73.33%) and yellowish structureless areas (60%). Yellowish structures in sebaceous carcinomas are the main dermoscopic findings to differentiate squamous cell and basal cell carcinomas (P < 0.001), whereas purplish globules, shiny white blotches and strands and whitish-pink area distinguish sebaceous carcinomas from other sebaceous tumors (P < 0.05).

show abstract

Section: Discussionsupporting

confidence: 64%

Section: Discussionsupporting

confidence: 48%

Dermoscopic features and differential diagnosis of sebaceous carcinoma

Cheng

Kuo

2020

The Journal of Dermatology

View full text Add to dashboard Cite

show abstract

“…However, our results showed that the major dermoscopic feature of the sebaceous carcinoma was "polymorphous vessels" with homogenous yellow backgrounds, which indicates that abundant blood vessels are located between the tumor nests and the epidermis and that the tumor nests include sebum, while sebaceoma usually manifests arborizing telangiectasias at the periphery of the lesion. 4,5 Another finding in our case is the variably sized bluish globular-like structures, which is one of the main dermoscopic features of clonal seborrheic keratosis. 2 To elucidate the precise dermoscopic features of sebaceous carcinoma, detailed analyses of dermoscopic findings correlated with histopathological findings would be imperative.…”

mentioning

confidence: 51%

Extraocular sebaceous carcinoma in association with a clonal seborrheic keratosis: Dermoscopic features

Iikawa

Namiki

Arima

et al. 2015

The Journal of Dermatology

View full text Add to dashboard Cite

Extraocular sebaceous carcinoma in association with a clonal seborrheic keratosis: Dermoscopic featuresDear Editor, The clinical diagnosis of extraocular sebaceous carcinoma is challenging due to the lack of specific clinical manifestations of this neoplasm. However, previous reports of extraocular sebaceous carcinomas using dermoscopy have been limited. 1 Here, we present a case of an extraocular sebaceous carcinoma in association with a clonal seborrheic keratosis and we describe its dermoscopic features.A 75-year-old woman presented with a tumor in a black plaque on her abdomen. The patient had a history of burn injury on her abdomen 30 years prior. Her burn scar had gradually become black and then developed a tumor with bleeding 3 months earlier.Physical examination revealed a 20 mm 9 12 mm black keratotic plaque with an elevated tumor in the center of her abdomen infraumbilically (Fig. 1a). Dermoscopic examination revealed that this lesion had two components: polymorphous vessels with homogenous yellow backgrounds in the center and blue-gray globules at the periphery (Fig. 1b). The polymorphous vessels were composed of linear irregular vessels, glomerular vessels and hairpin-like vessels (Fig. 1c). At the periphery, similar findings with bluegray structures of various size and shape were observed. Figure 1. (a) A 20 mm 9 12 mm black keratotic plaque with an elevated tumor on the patient's abdomen. (b) Dermoscopic features showing two components: polymorphous vessels with homogenous yellow backgrounds in the center and blue-gray globules at the periphery. The dotted line indicates the section of the histopathological specimen. The two dashed boxes indicate magnified dermoscopic photos shown in (c) and (d). (c) Dermoscopic features of the component of polymorphous vessels with homogenous yellow backgrounds. The dotted line indicates the section of the histopathological specimen. (d) Dermoscopic features of blue-gray globules at the periphery of the lesion. These multiple blue-gray globules were variably sized bluish globular-like structures as described by Longo et al. 2 The dotted line indicates the section of the histopathological specimen. (e) Histopathological examination at low magnification showing tumor nests of the sebaceous carcinoma on the right side and the clonal seborrheic keratosis on the left side. The dashed boxes (right and left) indicate areas shown in (f) and (h), respectively (hematoxylin-eosin [HE], original magnification 940). (f) Tumor nests composed of lobular aggregations (HE, 9100). (g) Tumor nests consisting of atypical neoplastic cells, some of which had vacuolated cytoplasm and scalloped nuclei (HE, 9400). (h) Intraepidermal nests of basaloid or pale cells with extensive pigmentation at the periphery (HE, 9100). (i) Immunohistochemistry with adipophilin (9100).

show abstract

“…Dermoscopy of sebaceoma may present an amorphous yellowish-erythematous area with or without ulcerations, with centripetally branched arboriform vessels. The amorphous yellowish-erythematous area may be an important finding suggesting the sebaceous etiology of the lesion 3, 4…”

Section: Discussionmentioning

confidence: 99%