Use of Derivative UV-Spectrophotometry for Stability Studies of (Dimethylamino) Ethyl O-Chloro, P-Dimethylamino(Sulphamoxylphenoxy)-Acetate Hydrochloride in Aqueous Solution

Ultraviolet and Absorption Light Spectrometry

“…A new spectrophotometric method for the analysis of binary mixtures of the flavonoids chrisin and quercetin using first-and second-order derivatives of the spectra ratio has been described (118). The third-derivative method using the zerocrossing technique has been employed to effect the simultaneous determination of (dimethylamino)ethyl (o-chloro-p-(dimethylamino)sulfonylphenoxy)acetate hydrochloride and its major hydrolytic decomposition product (o-chloro-p-(dimethylamino)sulfonylphenoxy)acetic acid (119). One paper has described a multiwavelength linear regression derivative spectrophotometric method for the determination phenol, hydroquinone, and catechol (120).…”

Analysis of Salbutamol and Related Impurities by Derivative Spectrometry

“…Ultraviolet derivative spectrometry [8,9] has been applied successfully in pharmaceutical analysis for the determination of drugs in the presence of their degradation products [10,11] and the analogs of related impurity or impurities in the presence of the drug [12] .…”