Use of contraindicated antiretroviral drugs in people with <scp>HIV</scp>/<scp>HCV</scp> coinfections receiving <scp>HCV</scp> treatment with direct‐acting antivirals—Results from the <scp>EuroSIDA</scp> study

Nikolaichuk, Myroslava; Mocroft, Amanda; Wandeler, Gilles; Szlávik, János; Gottfreðsson, Magnús; Reikvam, Dag Henrik; Svedhem, Veronica; Elinav, Hila; Laguno, Montserrat; Kamal, Mehnaz; Devitt, Emma; Chkhartishvili, Nikoloz; Behrens, Georg M. N.; Bogner, Johannes R.; Viard, Jean‐Paul; Winston, Alan; Benfield, Thomas; Leen, Clifford; Fursa, Olga; Rockstroh, Jürgen K.; Peters, Lars

doi:10.1111/hiv.13357

Cited by 2 publications

(1 citation statement)

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“…In addition, the coadministration of efavirenz, etravirine, and nevirapine is not recommended as they can reduce exposure to glecaprevir/pibrentasvir. There is some evidence that administering potentially interacting drugs does not affect the effectiveness of DAAs, but this can now more easily be avoided as noninteracting antiretroviral drugs are increasingly available [28].…”

Section: Hepatitis C Virusmentioning

confidence: 99%

Liver Transplantation in People Living with HIV: Still an Experimental Procedure or Standard of Care?

Lynch,

Russo

2023

Life

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Liver transplantation (LT) is the only curative treatment for various liver diseases, including acute liver failure, end-stage liver disease, and selected unresectable liver malignancies. Combination antiretroviral therapy has improved outcomes for people living with HIV (PLWH), transforming the status of acquired immune deficiency syndrome from a fatal disease to a chronic and manageable condition. These powerful antiviral therapies have not only increased the number of HIV+ enlisted patients by improving their survival but also made the use of HIV+ organs a viable option. In this review, we summarise current knowledge on the peculiarities of liver transplantation in PLWH. In particular, we focus on the indications, contraindications, specific considerations for treatment, and outcomes of LT in PLWH. Finally, we present available preliminary data on the use of HIV+ liver allografts.

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Section: Hepatitis C Virusmentioning

confidence: 99%