Use of comprehensive geriatric assessment in older cancer patients:

Extermann, Martine; Aapro, Matti; Bernabei, Roberto; Cohen, Harvey Jay; Droz, Jean Pierre; Lichtman, Stuart M.; Mor, Vincent; Monfardini, S.; Repetto, Lazzaro; Sørbye, Liv Wergeland; Topinková, Eva

doi:10.1016/j.critrevonc.2005.06.003

Cited by 977 publications

(192 citation statements)

References 96 publications

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“…CGA is a multidisciplinary and global approach dedicated to predict the mortality and morbidity of elderly patients diagnosed with cancer and to adapt the cancer treatment in this specific population (8). The international society of geriatric oncology (SIOG) recommends the use of several tools to assess the functional, psychological, cognitive and nutrition status, the risk of falls and the number and severity of co-morbidities (9). As this evaluation may be long and difficult in a busy routine practice, SIOG developed simplified screening tools to identify elderly patients in need of the complete CGA.…”

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confidence: 99%

Elderly selection on geriatric index assessment

Tomasini

Mascaux²

2016

Ann. Transl. Med.

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confidence: 99%

Elderly selection on geriatric index assessment

Tomasini

Mascaux²

2016

Ann. Transl. Med.

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“…Oncologists are faced with the challenge of determining the optimal treatment for these patients, with their heterogeneity in comorbidity, physical reserve, disabilities, and geriatric conditions. In this context, a myriad of editorials and review articles have been published, endorsing the use of a comprehensive geriatric assessment (CGA) in geriatric oncology [2][3][4][5][6][7][8][9]. A CGA is a systematic procedure used to objectively appraise the health status of older people, focusing on somatic, functional, and psychosocial domains [2] and aimed at constructing a multidisciplinary treatment plan.…”

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confidence: 99%

The Value of Geriatric Assessments in Predicting Treatment Tolerance and All-Cause Mortality in Older Patients With Cancer

Hamaker¹,

et al. 2012

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After completing this course, the reader will be able to:1. Describe the predictive value of geriatric assessments for survival in older cancer patients.2. Describe the predictive value of geriatric assessments for treatment tolerance (such as toxicity of chemotherapy and perioperative complications) in older cancer patients. Explain the concept of frailty compared to individual geriatric conditions.This article is available for continuing medical education credit at CME.TheOncologist.com. CME CME ABSTRACTBackground. Awareness of the use of geriatric assessments for older patients with cancer is increasing. The aim of this review is to summarize all available evidence on the association between geriatric assessments and relevant oncologic outcomes. Method. A systematic search was conducted in Medline and Embase of studies on geriatric assessment in oncology, focusing on the association between baseline assessment and outcome.Results. The literature search identified 2008 reports; 51 publications from 37 studies were selected for inclu-

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“…Also the geriatric patients merit additional careful consideration in view of higher prevalence of co-morbidities and depletion of their physiological reserve which affects therapy adversely. Therefore, as recommended by the Society of Geriatric Oncology, a thorough objective assessment of elderly patients is mandatory (23). This would help to break through the barrier of ageism.…”

Section: Discussionmentioning

confidence: 99%

Treatment Compliance and Outcome in Geriatric Patients with Locally Advanced Non-Small Cell Lung Cancer: Experience from India

et al. 2016

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Objectives: To evaluate treatment compliance, toxicity and survival in geriatric patients (≥65 years) with locally advanced nonsmall cell lung cancer (LA-NSCLC).Methods: Departmental archive was collected for the details of demographics, treatment and outcome in elderly patients with LA-NSCLC (2008 -2013) (n = 96). Both progression-free survival (PFS) and overall survival (OS) were evaluated using Kaplan-Meier method. Acute and late morbidity were scored using common terminology criteria for adverse events version 4, radiation therapy and oncology group late morbidity scoring system. Results:Overall treatment completion rate was 65%. The rates of acute grade ≥ 3 hematologic and non-hematologic toxicities were 20% and 17% respectively. Overall rate of late toxicity was 12.5%. The median PFS and OS values were 7.4 months and 10.54 months, respectively. Patients with multiple comorbidities, poor socio-economic background and serum albumin level (< 3.5g/dL) were observed to have poor survival. Survival was lower for non-compliant patients. Conclusions:Curative multi-modality therapy in elderly patients with LA-NSCLC is a challenging task. They are susceptible to poor compliance, treatment-associated toxicities and poor survival.

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Use of comprehensive geriatric assessment in older cancer patients:

Cited by 977 publications

References 96 publications

Elderly selection on geriatric index assessment

Elderly selection on geriatric index assessment

The Value of Geriatric Assessments in Predicting Treatment Tolerance and All-Cause Mortality in Older Patients With Cancer

Treatment Compliance and Outcome in Geriatric Patients with Locally Advanced Non-Small Cell Lung Cancer: Experience from India

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