Use of Complementary Medicine by Adult Patients Participating in HIV/AIDS Clinical Trials

Sparber, Andrew; Wootton, Jacqueline C.; Bauer, Larry; Curt, Gregory A.; Eisenberg, David M.; Levin, Tina; Steinberg, Seth M.

doi:10.1089/acm.2000.6.415

Cited by 179 publications

(190 citation statements)

References 12 publications

Supporting

Mentioning

167

Contrasting

Unclassified

Order By: Relevance

“…CAM may add to or seek to replace conventional care, and recent commentators have used the phrase "integrative medicine" to foster more open debate. In a sample of HIV/AIDS patients enrolled in a clinical trial at the National Institutes of Health (NIH), 91% had used at least one CAM therapy [3]. A number of reports of the use of CAM among oncology patients cite a prevalence of 1 in 3.…”

Section: Discussion Prevalence and Costs Of Usementioning

confidence: 99%

“…They intimate that CAM resembles that antiquated and unjust system. Of the myriad reasons cancer patients seek CAM, a sense of helplessness, incomplete trust in physician, a changed outlook since cancer diagnosis, and a deteriorating functional quality of life are among the most generally voiced [45,51]. Patients battling serious ailments valued CAM for its medicinal potential.…”

Section: Harnessing Hope: Motives For Cam Usementioning

confidence: 99%

See 1 more Smart Citation

Complementary, Alternative, Integrative, or Unconventional Medicine?

et al. 2001

View full text Add to dashboard Cite

The Oncologist ® Schwartz Center RoundsMrs. J is an active and health conscious 45-year-old woman with an unremarkable medical history who presented with prolonged abdominal bloating and increasing abdominal girth. Evaluation revealed a large ovarian mass and ascites. The tumor marker CA-125 level was 2,068 U/ml. At surgical exploration she was found to have stage IIc grade 2-3 serous papillary ovarian carcinoma and was optimally cytoreduced. She received three cycles of paclitaxel and carboplatin chemotherapy. At re-evaluation Mrs. J had persisting elevation of CA-125 and was found to have ascites fluid on computerized tomography (CT) scan. She was referred for experimental therapies.Liver-function-test abnormalities were moderately abnormal. She drank very little alcohol and had no history of hepatitis. She felt entirely well and had no symptoms of progressive ovarian cancer. She was actively involved in aerobics and exercise.In light of her good prognostic factors and the ambiguous clinical picture, laparoscopy was recommended and was unremarkable. Washings and biopsy were negative for cancer confirming pathological complete remission.After the surgery, more careful questioning revealed that she had been taking megadoses of vitamin A for 3 months prior to the diagnosis. When she was informed that

show abstract

Section: Discussion Prevalence and Costs Of Usementioning

confidence: 99%

Section: Harnessing Hope: Motives For Cam Usementioning

confidence: 99%

Complementary, Alternative, Integrative, or Unconventional Medicine?

et al. 2001

View full text Add to dashboard Cite

show abstract

“…More recent studies have reported an even higher prevalence of between 70 and 80% (Richardson et al, 2000;Bernstein and Grasso, 2001;Ashikaga et al, 2002). The nature of CAMs used, for example, vitamins and other supplements, herbal remedies, physical and psychological treatments, also varies greatly (Risberg et al, 1998;Richardson et al, 2000;Sparber et al, 2000;Bernstein and Grasso, 2001;Ashikaga et al, 2002).…”

mentioning

confidence: 99%

“…The reasons for CAM use have been widely investigated. Patients often wish to combine conventional and CAM approaches to improve their quality of life, to counter side effects, to achieve a sense of control and to match their life style with their world view (Austin, 1998;Sparber et al, 2000;Kessler et al, 2001).…”

mentioning

confidence: 99%

Potential health risks of complementary alternative medicines in cancer patients

et al. 2004

View full text Add to dashboard Cite

Many cancer patients use complementary alternative medicines (CAMs) but may not be aware of the potential risks. There are no studies quantifying such risks, but there is some evidence of patient risk from case reports in the literature. A cross-sectional survey of patients attending the outpatient department at a specialist cancer centre was carried out to establish a pattern of herbal remedy or supplement use and to identify potential adverse side effects or drug interactions with conventional medicines. If potential risks were identified, a health warning was issued by a pharmacist. A total of 318 patients participated in the study. Of these, 164 (51.6%) took CAMs, and 133 different combinations were recorded. Of these, 10.4% only took herbal remedies, 42.1% only supplements and 47.6% a combination of both. In all, 18 (11.0%) reported supplements in higher than recommended doses. Health warnings were issued to 20 (12.2%) patients. Most warnings concerned echinacea in patients with lymphoma. Further warnings were issued for cod liver/fish oil, evening primrose oil, gingko, garlic, ginseng, kava kava and beta-carotene. In conclusion, medical practitioners need to be able to identify the potential risks of CAMs. Equally, patients should be encouraged to disclose their use. Also, more research is needed to quantify the actual health risks.

show abstract

“…They, like their patients, believe that CAM modalities can decrease side effects, but do not expect CAM to boost immunity or improve quality of life [17]. Strengthening the immune system is a common reason cited by patients, but not physicians, for DS use [18,19], as is a desire to decrease medication complications or relieve other symptoms, such as anxiety or depression [8,18]. While desire for a cure is less often stated as a reason, prevention of recurrence is a common reason for breast cancer patients to use CAM [19].…”

mentioning

confidence: 99%