Use of Commerical Dacron Fabric in the Repair of Inguinal Hernias and Abdominal Wall Defects

Wolstenholme, James T.

doi:10.1001/archsurg.1956.01280060104024

Cited by 39 publications

(14 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Polyester fibers are extremely strong, durable and resistant to most chemicals. PET surgical meshes were first exploited in the 1960s for the repair of inguinal and abdominal hernias, 33 but they are not widely available at present, probably due to conflicting data reported in literature about their safety and efficacy. Short-term animal studies of implanted PET prosthetics have demonstrated several advantages, including higher rates of tissue regeneration than PP meshes.…”

Section: Polyestermentioning

confidence: 99%

Synthetic surgical meshes used in abdominal wall surgery: Part I-materials and structural conformation

Todros

Pavan

Natali

2015

J. Biomed. Mater. Res.

View full text Add to dashboard Cite

Surgical implants are commonly used in abdominal wall surgery for hernia repair. Many different prostheses are currently offered to surgeons, comprising permanent synthetic polymer meshes and biologic scaffolds. There is a wide range of synthetic meshes currently available on the market with differing chemical compositions, fiber conformations, and mesh textures. These chemical and structural characteristics determine a specific biochemical and mechanical behavior and play a crucial role in guaranteeing a successful post-operative outcome. Although an increasing number of studies report on the structural and mechanical properties of synthetic surgical meshes, nowadays there are no consistent guidelines for the evaluation of mechanical biocompatibility or common criteria for the selection of prostheses. The aim of this work is to review synthetic meshes by considering the extensive bibliography documentation of their use in abdominal wall surgery, taking into account their material and structural properties, in Part I, and their mechanical behavior, in Part II. The main materials available for the manufacture of polymeric meshes are described, including references to their chemical composition, fiber conformation, and textile structural properties. These characteristics are decisive for the evaluation of mesh-tissue interaction process, including foreign body response, mesh encapsulation, infection, and adhesion formation. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2015

show abstract

Section: Polyestermentioning

confidence: 99%

Synthetic surgical meshes used in abdominal wall surgery: Part I-materials and structural conformation

Todros

Pavan

Natali

2015

J. Biomed. Mater. Res.

View full text Add to dashboard Cite

show abstract

“…Surgical meshes have been used routinely for various soft tissue reinforcement applications since the introduction of Dacron ® (polyethylene terephthalate, PET) and Marlex ® (polypropylene, PP) in the late 1950s [1, 2]. For hernia repair, polypropylene meshes in particular have been considered the standard material for fabrication of prosthetic meshes used for the tension-free hernia repair described by Lichtenstein et al [3] in 1989 as well as for other surgical techniques.…”

Section: Introductionmentioning

confidence: 99%

Three-year results from a preclinical implantation study of a long-term resorbable surgical mesh with time-dependent mechanical characteristics

Hjort¹,

Mathisen²,

Alves

et al. 2011

Hernia

View full text Add to dashboard Cite

PurposeThe purpose of this study was to evaluate the biocompatibility, local tissue effects and performance of a synthetic long-term resorbable test mesh (TIGR® Matrix Surgical Mesh) compared to a non-resorbable polypropylene control mesh following implantation in a sheep model.MethodsFull-thickness abdominal wall defects were created in 14 sheep and subsequently repaired using test or control meshes. Sacrifices were made at 4, 9, 15, 24 and 36 months and results in terms of macroscopic observations, histology and collagen analysis are described for 4, 9, 15, 24 and 36 months.ResultsThe overall biocompatibility was good, and equivalent in the test and control meshes while the resorbable mesh was characterized by a collagen deposition more similar to native connective tissue and an increased thickness of the integrating tissue. The control polypropylene mesh provoked a typical chronic inflammation persistent over the 36-month study period. As the resorbable test mesh gradually degraded it was replaced by a newly formed collagen matrix with an increasing ratio of collagen type I/III, indicating a continuous remodeling of the collagen towards a strong connective tissue. After 36 months, the test mesh was fully resorbed and only microscopic implant residues could be found in the tissue.ConclusionsThis study suggests that the concept of a long-term resorbable mesh with time-dependent mechanical characteristics offers new possibilities for soft tissue repair and reinforcement.

show abstract

“…Burke 9 introduziu o tântalo em cirurgia, abandonado após a comprovação de sua tendência à fragmentação e frequentes complicações, como fístulas no intestino delgado, ulcerações e extrusão de fragmentos do metal por meio do peritônio e da pele 10 . A partir da década de cinquenta, uma variedade de polímeros sintéticos ou disponíveis, como o polietileno tereftalato (Dacron ® ) 11 , o polipropileno monofilamentar (Marlex ® ) e o polipropileno com filamento duplo (Prolene ® ) 12 , o politetrafluoretileno multifilamentar (Teflon ® ) não-poroso, abandonado precocemente, e o polímero de politetrafluoretileno expandido (ePTFE), que apresenta forma porosa, resultando em uma diminuição da reação tecidual tipo corpo estranho 13 . Posteriormente, o politetrafluoretileno evoluiu para uma forma denominada Gore-tex ®8 , que se incorporou ao grupo de materiais usados para as reconstruções da parede abdominal.…”

Section: Introductionunclassified

Hemicelulose em reconstrução da parede abdominal em ratos

Andrade¹,

Cavalcanti²,

Mota³

et al. 2011

Rev. Bras. Cir. Plást. (Impr.)

View full text Add to dashboard Cite

Rev. Bras. Cir. Plást. 2011; 26(1): 104-15 104 Andrade FAG et al. Hemicelulose em reconstrução da parede abdominal em ratosReconstruction of the abdominal wall in rats with hemicellulose RESUMO Introdução: As perdas de substância da parede abdominal (PSPA) revestem-se de importância clínica e cirúrgica em função da alta frequência com que ocorrem, do sofrimento que produzem e do alto custo dos tratamentos atualmente ministrados. Nos últimos anos, tem-se observado o desenvolvimento de novas técnicas para a resolução das perdas de substância da PSPA, entre as quais se incluem a realização de retalhos e o uso de materiais biocompatíveis e sintéticos. Método: Esse estudo experimental aleatório e não controlado avaliou o uso da hemicelulose para a reparação das PSPA em 40 ratos Wistar EPM III, femêos. Os animais foram divididos em quatro grupos experimentais de estudo: I (n=10), II (n=10), III = (n=10) e IV (n=10). Todos os animais foram submetidos a anestesia geral utilizando-se o tiopental sódico, via intraperitonial. Foi provocada uma lesão de 2,0 x 3,0cm no tecido músculo-aponeurótico e peritônio da região anterior do abdome. A aposição da película de hemicelulose sobre a lesão foi realizada superpondo-se 15 películas de 2,0 x 3,0cm, umedecidas em soro fisiológico a 0,9%. A película foi fixada à parede muscular adjacente e, em seguida, foi realizada a síntese da pele e panículo carnoso por meio de sutura contínua com fio de náilon de número cinco zeros. A eutanásia dos animais dos grupos I (n=10), II (n=10), III (n=10) e IV (n=10) foi realizada após 3, 28, 35 e 240 dias, respectivamente. Conclusão: Esse estudo concluiu que a hemicelulose foi eficiente em reparar as grandes perdas da parede abdominal em ratos.Descritores: Parede abdominal/cirurgia. Implantes experimentais. Ratos. Histologia. ABSTRACTIntroduction: Substance losses of abdominal wall (SLAW) has a vital clinical and surgical importance due to the high frequency which they occur, the suffering they cause, the challenge of treatment and the high cost of treatment administered today. In the last years, has been observed the development of new techniques to resolve SLAW, some which include the making of flaps and the use of biocompatible and synthetic materials. Methods: This random experimental and uncontrolled study evaluated the use of hemicellulose as a repair of SLAW in 40 EPM III Wistar female rats. The animals were divided in four experimental study groups: I (n=10), II (n=10), III (n=10), IV (n=10). All the animals were submitted to general anesthesia using sodium thiopental, via intraperitoneal. A lesion of aponeurotic muscle tissue and peritoneal from the region anterior abdominal was made. The placing of hemicellulose pellicle over the lesion was performed overlapping fifteen pellicles (2.0 x 3.0 cm each), bathed in 0.9% saline solution. The pellicle was fixed to adjacent muscle wall, the subcutaneous and skin was sutured by continuous suturing with 5-0 nylon suture. The provoked death (euthanasia) of the animals in each group -I (n=10), II (n=1...

show abstract

Use of Commerical Dacron Fabric in the Repair of Inguinal Hernias and Abdominal Wall Defects

Cited by 39 publications

References 7 publications

Synthetic surgical meshes used in abdominal wall surgery: Part I-materials and structural conformation

Synthetic surgical meshes used in abdominal wall surgery: Part I-materials and structural conformation

Three-year results from a preclinical implantation study of a long-term resorbable surgical mesh with time-dependent mechanical characteristics

Hemicelulose em reconstrução da parede abdominal em ratos

Contact Info

Product

Resources

About