Use of an infrared temperature monitoring system to determine optimal temperature for arterial repair using light-activated surgical adhesive

Soller, Eric C.; Hoffman, Grant T.; McNally-Heintzelman, Karen M.

doi:10.1117/12.476388

Cited by 1 publication

(3 citation statements)

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“…phore concentrations as a function of welding strength, respectively. The majority of ssLAVW studies were performed in vitro as ssLAVR of small-and medium-sized vessels and used either a 670-nm or an 806-810-nm diode laser [86,[93][94][95][96][97][98][99][100][101][102][103]. Figure 9 shows the improvement in welding strength with increasing power and irradiance.…”

Section: Laser-scaffold Interactionsmentioning

confidence: 99%

“…Figure 9 and 10 depict the lasing parameters and chromo- Figure 9. Breaking force obtained with ssLAVR performed at different powers (A) and irradiances (B) ssLAVR in [58,101,102] was performed with poly(lactic-co-glycolic acid) (PLGA) scaffolds, indocyanine green-containing 50% bovine serum albumin (BSA) solder and an 806-nm diode laser. The ssLAVR in [98] was performed with a poly(ε-caprolactone) (PCL) scaffold, a solder containing 48% BSA, 0.5% methylene blue, and 3% hydroxypropylmethylcellulose and a 670-nm diode laser.…”

Section: Laser-scaffold Interactionsmentioning

confidence: 99%

“…Furthermore, the flexibility of the scaffold is more favorable for vascular applications than solid solder films [58]. ssLAVW comprises the use of a polymeric scaffold to enhance cohesive bonding of the liquid solder during sLAVW [93][94][95][96][97][98][99][100][101][102][103]108]. A semi-porous scaffold composed of biocompatible polymeric material is drenched in chromophore-containing solder, placed over the coaptation, and irradiated.…”

Section: Drawbacks Of Slavwmentioning

confidence: 99%

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Laser-assisted vessel welding: state of the art and future outlook

Pabittei

Boon

Heger

et al. 2015

JCTRes

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Laser-assisted vascular welding (LAVW) is an experimental technique being developed as an alternative to suture anastomosis. In comparison to mechanical anastomosis, LAVW is less traumatic, non-immunogenic, provides immediate water tight sealant, and possibly a faster and easier procedure for minimally invasive surgery. This review focuses on technical advances to improve welding strength and to reduce thermal damage in LAVW. In terms of welding strength, LAVW has evolved from the photothermally-induced microvascular anastomosis, requiring stay sutures to support welding strength, to sutureless anastomoses of medium-sized vessels, withstanding physiological and supraphysiological pressure. Further improvements in anastomotic strength could be achieved by the use of chromophore-containing albumin solder and the employment of (biocompatible) polymeric scaffolds. The anastomotic strength and the stability of welds achieved with such a modality, referred to as scaffold-and solder-enhanced LAVW (ssLAVW), are dependent on the intermolecular bonding of solder molecules (cohesive bonding) and the bonding between solder and tissue collagen (adhesive bonding). Presently, the challenges of ssLAVW include (1) obtaining an optimal balance between cohesive and adhesive bonding and (2) minimizing thermal damage. The modulation of thermodynamics during welding, the application of semi-solid solder, and the use of a scaffold that supports both cohesive and adhesive strength are essential to improve welding strength and to limit thermal damage.

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