Use of an electronic stimulator for the treatment of dry mouth

Weiss, W.W.; Brenman, Henry S.; Katz, Philip O.; Bennett, Joel A.

doi:10.1016/0278-2391(86)90219-3

Cited by 41 publications

(33 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…And also in a study by Weiss et al [8] who reported the use of an electronic stimulator as a method for increasing salivary production. Following a visual NS=Non-significant examination of the oral cavity as well as a gloved finger test to determine the presence of moisture (any reflection was considered a sign of wetness), patients were administered a 3-min stimulus to the tongue and roof of the mouth with the probe (electrodes) of the hand-held stimulator.…”

Section: Discussionmentioning

confidence: 95%

“…[7] The results of preliminary investigations of non-invasive electronic stimulation of reflex salivation in xerostomic patients have been encouraging. [3,8] An original investigation using non-invasive electrical stimulation for treatment and prevention of radiation side-effects in patients undergoing radiotherapy for carcinoma of head and neck showed promising results. [9] Research in this area has been sparse and hence this study was undertaken to evaluate the effectiveness of a TENS unit in stimulating the whole salivary flow rate in radiation induced xerostomia patients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of effect of transcutaneous electrical nerve stimulation on salivary flow rate in radiation induced xerostomia patients: A pilot study

Lakshman¹,

Babu

Rao

2015

J Can Res Ther

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Evaluation of effect of transcutaneous electrical nerve stimulation on salivary flow rate in radiation induced xerostomia patients: A pilot study

Lakshman¹,

Babu

Rao

2015

J Can Res Ther

View full text Add to dashboard Cite

show abstract

“…In two clinical studies of patients with xerostomia resulting from various causes, there was significant improvement in salivary production and symptoms associated with xerostomia after electrical stimulation using a device applied to the tongue and hard palate 34, 35 . Laboratory studies have shown that electrical stimulation of the parasympathetic nerve to the parotid and submandibular glands in rats causes a mitogenic response as indicated by an increase in tritiated thymidine uptake of the glands 36 .…”

Section: Discussionmentioning

confidence: 99%

Phase 2 results from Radiation Therapy Oncology Group Study 0537

Wong

James

Sagar

et al. 2012

Cancer

View full text Add to dashboard Cite

Purpose This phase II component of a multi-institutional phase II/III randomized trial assessed the feasibility and preliminary efficacy of acupuncture-like transcutaneous electrical nerve stimulation (ALTENS) in reducing radiation-induced xerostomia. Methods Head and neck cancer patients who were 3–24 months from completing radiotherapy ± chemotherapy (RT±C) and experiencing xerostomia symptoms with basal whole saliva production ≥0.1 ml/min and without recurrence were eligible. Patients received twice weekly ALTENS sessions (24 over 12 weeks) using a Codetron™ unit. The primary objective assessed the feasibility of ALTENS treatment. A patient was considered compliant if 19/24 ALTENS were delivered, with a targeted 85% compliance rate. Secondary objectives measured treatment-related toxicities and ALTENS effect on overall radiation-induced xerostomia burden using the University of Michigan Xerostomia-Related Quality of Life Scale (XeQOLS). Results Of 48 accrued patients, 47 were evaluable. Median age was 60 years; 84% were male, 70% completed RT±C for > 12 months and 21% had received prior pilocarpine. All ALTENS sessions were completed in 34 patients, but 9 and 1 completed 20–23 and 19 sessions respectively, representing a 94% total compliance rate. 6-month XeQOLS scores were available for 35 patients; 30 (86%) achieved a positive treatment response with a mean reduction of 35.9% (SD 36.1). Five patients developed grade 1–2 gastrointestinal toxicity and one had grade 1 pain event. Conclusions ALTENS treatment for radiation-induced xerostomia can be uniformly delivered in a cooperative multicenter setting and has possible beneficial treatment response. Given these results, the phase III component of this study was initiated.

show abstract

“…One study (19) included in this systematic review presents improvement in four of nine patients treated with acupuncture at the 1‐year follow‐up. Other treatments developed to treat xerostomia have not been able to show long‐lasting results (4, 5).…”

Section: Discussionmentioning

confidence: 99%

Acupuncture in xerostomia – a systematic review

Jedel¹

2005

J of Oral Rehabilitation

View full text Add to dashboard Cite

The aim of this systematic review was to assess the efficacy of acupuncture in the management of xerostomia. Assessing quality of studies aim to efficiently integrate valid information and provide a basis for sound decision making based on the best available evidence. Articles of controlled clinical trials evaluating the efficacy of acupuncture in the management of xerostomia were obtained by searching through the databases MEDLINE and Cochrane Central Register of Controlled Trials to September 2003. Three articles met the criteria for inclusion and a criteria list was used to assess the quality of these studies. The studies were considered to be of high quality or low quality in accordance with the criteria list utilized. The results of the trials were considered positive, negative or indifferent based on statistically significant between group differences. The criteria list utilized indicate that one of the three studies was of high quality and it presents indifferent results. One of the two studies of low quality presents positive results and one presents indifferent results. An analysis of the results degree of evidence resulted in no evidence for the efficacy of acupuncture in the management of xerostomia. This systematic review shows that there is no evidence for the efficacy of acupuncture in the management of xerostomia. There is a need for future high quality randomized controlled trials.

show abstract

Use of an electronic stimulator for the treatment of dry mouth

Cited by 41 publications

References 3 publications

Evaluation of effect of transcutaneous electrical nerve stimulation on salivary flow rate in radiation induced xerostomia patients: A pilot study

Evaluation of effect of transcutaneous electrical nerve stimulation on salivary flow rate in radiation induced xerostomia patients: A pilot study

Phase 2 results from Radiation Therapy Oncology Group Study 0537

Acupuncture in xerostomia – a systematic review

Contact Info

Product

Resources

About