Use of alcohol and illicit drugs by trauma patients in Sao Paulo, Brazil

Bombana, Henrique Silva; Bogstrand, Stig Tore; Gjerde, Hallvard; Jamt, Ragnhild Elén Gjulem; Carvalho, Heráclito Barbosa; Andreuccetti, Gabriel; Bernini, Celso de Oliveira; Muñoz, Daniel Romero; Leyton, Vilma; Greve, Julia Maria D’Andréa

doi:10.1016/j.injury.2021.10.032

Cited by 14 publications

(9 citation statements)

References 43 publications

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“…Only two studies addressed the prevalence of cocaine and amphetamines, with both studies reporting little to no use of these drugs. Notably, the low prevalence of cocaine reported in this review is not consistent with a recent study from Brazil, which reported a 13% prevalence of cocaine use in patients with fall-related injuries based on blood tests as opposed to urine tests 57. Findings regarding cannabis use were inconsistent, but ultimately difficult to compare since testing methods were not well reported, particularly regarding the timing of testing.…”

Section: Discussioncontrasting

confidence: 90%

Prevalence of alcohol and other drug use in patients presenting to hospital for fall-related injuries: a systematic review

et al. 2022

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BackgroundAlcohol and other drug (AOD) use is a key preventable risk factor for serious injuries. Prevention strategies to date have largely focused on transport injuries, despite AOD use being a significant risk factor for other injury causes, including falls. This systematic review aimed to report the prevalence of AOD use in patients presenting to hospital for fall-related injuries.MethodsThis systematic review includes studies published in English after the year 2010 that objectively measured the prevalence of AOD use in patients presenting to hospital for a fall-related injury. Screening, data extraction and risk of bias assessments were completed by two independent reviewers. Data were presented using narrative synthesis and, where appropriate, meta-analyses.ResultsA total of 12 707 records were screened. Full texts were retrieved for 2042 records, of which 29 were included. Four studies reported the combined prevalence of any alcohol and/or drug use, generating a pooled prevalence estimate of 37% (95% CI 25% to 49%). Twenty-two records reported on the prevalence of acute alcohol use alone and nine reported specifically on the prevalence of drugs other than alcohol, with prevalence ranging from 2% to 57% and 7% to 46%, respectively. The variation in prevalence estimates likely resulted from differences in toxicology testing methods across studies.ConclusionsAOD exposure was common in hospitalised fall-related injuries. However, research addressing prevalence across different types of falls and the use of drugs other than alcohol was limited. Future research should address these areas to improve our understanding of which populations should be targeted in AOD and injury prevention strategies .PROSPERO registration numberCRD42020188746.

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Section: Discussioncontrasting

confidence: 90%

Prevalence of alcohol and other drug use in patients presenting to hospital for fall-related injuries: a systematic review

et al. 2022

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“…No que se refere ao tipo de veículo conduzido, segundo as informações das duas edições da PNS, as prevalências do hábito de beber e dirigir foram significativamente maiores entre os condutores de motocicleta. Trabalho realizado com pacientes atendidos em um serviço de emergência com lesões traumáticas em São Paulo mostrou que metade das lesões resultantes de acidentes de trânsito ocorreram entre motociclistas 19 . Já estudo realizado com motociclistas envolvidos em acidentes e internados no setor de traumatologia de um hospital de Recife, Pernambuco, revelou que o consumo de álcool antes do acidente foi relatado por 32,9% dos motociclistas e que o comportamento de dirigir após beber foi associado com o excesso de velocidade, o não uso do capacete e o fato de não possuir habilitação para motocicleta 20 , mostrando a necessidade de maiores intervenções educativas voltadas para esse tipo de condutor.…”

Section: Discussionunclassified

“…Nos Estados Unidos, dados do Centro de Administração Nacional de Segurança no Trânsito Rodoviário mostraram que, em 2016, 10.497 pessoas morreram em acidentes de trânsito causados pelo álcool, representando 28% de todas as mortes relacionadas ao trânsito 9 . No Brasil, informações do Departamento Nacional de Infraestrutura de Transportes (DNIT) mostraram que a Polícia Rodoviária Federal, no ano de 2017, flagrou 19.083 motoristas que dirigiram após consumir bebida alcoólica e que, no mesmo ano, 6.450 mil (33,8%) acidentes nas rodovias federais foram causados por motoristas alcoolizados, gerando 13 mil vítimas e cerca de mil mortes 10 .…”

Section: Introductionunclassified

O hábito de beber e dirigir no Brasil: Pesquisa Nacional de Saúde, 2013 e 2019

2022

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OBJETIVO: Investigar os fatores associados ao hábito de beber e dirigir, bem como estimar as variações nas prevalências desse comportamento entre os anos de 2013 e 2019, por meio das informações das duas edições da Pesquisa Nacional de Saúde (PNS). MÉTODOS: A PNS é um estudo transversal, de âmbito nacional e base domiciliar. Nos anos de 2013 e 2019, foram entrevistados, respectivamente, 60.202 e 85.854 indivíduos. Para investigar a associação entre o indicador “beber e dirigir” e as variáveis do estudo, as razões de chances (RC) brutas e ajustadas foram estimadas por meio de modelos de regressão logística. Para a comparação das prevalências entre os anos estudados, foi utilizado o teste Qui-Quadrado de Pearson ajustado pela correção de Rao-Scott (que leva em consideração o efeito do plano de amostragem) e convertido em uma estatística F, testada no nível de significância de 5%. RESULTADOS: A prevalência do hábito de beber e dirigir foi maior entre os homens no ano de 2013 (27,4%; IC95% 25,6–29,3%) e no ano de 2019 (20,5%; IC95% 19,4–21,7%) do que entre as mulheres (11,9%; IC95% 9,9–14,2% e 7,2%; IC95% 6,7–9,0%, respectivamente). Estimativas significativamente mais altas foram apresentadas por pessoas de 30 anos a 39 anos, que vivem sem companheiro(a), residentes em áreas rurais e condutores de motocicleta. Maiores prevalências de beber e dirigir foram encontradas entre homens que possuem maior rendimento. Entre os anos de 2013 e 2019, foi observado um decréscimo significativo no ato de beber e dirigir. Quanto ao envolvimento em acidentes de trânsito, as RC foram significativas (p < 0,01) nos anos estudados em ambos os sexos. DISCUSSÃO: Os resultados mostram a necessidade de dar continuidade às políticas de fiscalização de alcoolemia e educação no trânsito, com ações específicas dirigidas às áreas rurais e aos condutores de motocicletas.

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“…In contrast, women consume about 7 L/year [ 27 ], but such a pattern of global alcohol consumption has been modified, since women have augmented alcohol drinking over the years in amounts that are increasingly closer to men [ 28 ]. Of particular interest is the co-ingestion of alcohol with other drugs by abusers [ 2 , 10 , 13 ].…”

Section: Epidemiological Features Of Ethanol Plus Ketamine Consumptionmentioning

confidence: 99%

“…Drug abuse is an ancient human practice, which involves genetic and environmental factors, as well as a great complexity of neuronal circuitry [ 1 ]. Currently, the use of psychoactive substances has become a worldwide concern and public health issue, due to health risks and social problems [ 2 , 3 ]. In general, such involvement in drug misuse occurs early in life.…”

Section: Introductionmentioning

confidence: 99%

Ketamine plus Alcohol: What We Know and What We Can Expect about This

Kobayashi

Farias

Luz

et al. 2022

IJMS

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Drug abuse has become a public health concern. The misuse of ketamine, a psychedelic substance, has increased worldwide. In addition, the co-abuse with alcohol is frequently identified among misusers. Considering that ketamine and alcohol share several pharmacological targets, we hypothesize that the consumption of both psychoactive substances may synergically intensify the toxicological consequences, both under the effect of drugs available in body systems and during withdrawal. The aim of this review is to examine the toxicological mechanisms related to ketamine plus ethanol co-abuse, as well the consequences on cardiorespiratory, digestive, urinary, and central nervous systems. Furthermore, we provide a comprehensive discussion about the probable sites of shared molecular mechanisms that may elicit additional hazardous effects. Finally, we highlight the gaps of knowledge in this area, which deserves further research.

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Use of alcohol and illicit drugs by trauma patients in Sao Paulo, Brazil

Cited by 14 publications

References 43 publications

Prevalence of alcohol and other drug use in patients presenting to hospital for fall-related injuries: a systematic review

Prevalence of alcohol and other drug use in patients presenting to hospital for fall-related injuries: a systematic review

O hábito de beber e dirigir no Brasil: Pesquisa Nacional de Saúde, 2013 e 2019

Ketamine plus Alcohol: What We Know and What We Can Expect about This

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