Use of administrative data in healthcare research

Mazzali, Cristina; Duca, Piergiorgio

doi:10.1007/s11739-015-1213-9

Cited by 103 publications

(103 citation statements)

References 28 publications

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“…According to Park et al [35], about 70% of primary diagnosis codes concurred with medical records. Issues concerning studies involving administrative data are well described in Mazzali, C. and and P. Duca's study [36]. When the cases were confirmed by prescription codes and procedure code in addition to the diagnostic codes, the incidences would be lower than this study results.…”

Section: Strengths and Limitationsmentioning

confidence: 52%

The effect of the look-back period for estimating incidence using administrative data

Kim

Chae

Chung

et al. 2020

BMC Health Serv Res

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Background: The look-back period is needed to define baseline population for estimating incidence. However, short look-back period is known to overestimate incidence of diseases misclassifying prevalent cases to incident cases. The purpose of this study is to evaluate the impact of the various length of look-back period on the observed incidences of uterine leiomyoma, endometriosis and adenomyosis, and to estimate true incidences considering the misclassification errors in the longitudinal administrative data in Korea. Methods: A total of 319,608 women between 15 to 54 years of age in 2002 were selected from Korea National Health Insurance Services (KNHIS) cohort database. In order to minimize misclassification bias incurred when applying various length of look-back period, we used 11 years of claim data to estimate the incidence by equally setting the look-back period to 11 years for each year using prediction model. The association between the year of diagnosis and the number of prevalent cases with the misclassification rates by each look-back period was investigated. Based on the findings, prediction models on the proportion of misclassified incident cases were developed using multiple linear regression. Results: The proportion of misclassified incident cases of uterine leiomyoma, endometriosis and adenomyosis were 32.8, 10.4 and 13.6% respectively for the one-year look-back period in 2003. These numbers decreased to 6.3% in uterine leiomyoma and − 0.8% in both endometriosis and adenomyosis using all available look-back periods (11 years) in 2013. Conclusion: This study demonstrates approaches for estimating incidences considering the different proportion of misclassified cases for various length of look-back period. Although the prediction model used for estimation showed strong R-squared values, follow-up studies are required for validation of the study results.

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Section: Strengths and Limitationsmentioning

confidence: 52%

The effect of the look-back period for estimating incidence using administrative data

Kim

Chae

Chung

et al. 2020

BMC Health Serv Res

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“…Third, no supportive image reports and laboratory data from each medical record to confirm the diagnosis of collagen-associated adverse effects, we defined the outcome in this study by reviewing the registration of ICD-9-CM codes. The potential misclassification bias cannot be ruled out in our study [38]. Despite the potential limits, our study also has some strengths because the results of this study are based on a realworld database analysis.…”

Section: Discussionmentioning

confidence: 94%

The incidence of collagen-associated adverse events in pediatric population with the use of fluoroquinolones: a nationwide cohort study in Taiwan

Liu

et al. 2020

BMC Pediatr

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Background: To evaluate the safety of using fluoroquinolones in pediatric population in Taiwan. Methods: Patients aged 0~18 years old with fluoroquinolones prescriptions ≥5 consecutive days during year 2000 to 2013 were selected from the National Health Insurance Research Database, 4-time case number were selected as controls. We evaluated the patient's outcome after the use of fluoroquinolones by reviewing a newly diagnosis of the following collagen-associated adverse events by International Classification of Diseases, Ninth Revision, Clinical Modification codes, covering tendons rupture, retinal detachments, gastrointestinal tract perforation, aortic aneurysm or dissection. Results: Of the enrolled patients (n = 167,105), collagen-associated adverse effects developed in 85 cases (0.051%) in 6-month tracking, including 0.051% in the fluoroquinolones study cohort (17 in 33,421) and 0.051% (68 in 133, 684) in the fluoroquinolones free comparison cohort. The crude hazard ratio for collagen-associated adverse events in the fluoroquinolones group was 0.997 (0.586-1.696; p = 0.990). After adjusting for age, sex, catastrophic illness, low-income household, seasons, levels of urbanization, and healthcare, the corrected hazard ratio in 6-month tracking with FQs was 1.330 (95% CI; 0.778-2.276; p = 0.255). Conclusions: There is no significant difference of collagen-associated adverse effects between fluoroquinolones group and fluoroquinolones free group from our data. We propose that fluoroquinolones for pediatric population in clinical practice may be not so harmful as previous references reported.

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“…Administrative data, collected at the regional level, are at the basis of an important evaluation program at the national level, the National Outcome Project (PNE), which includes the evaluation of healthcare processes, interventions, providers, and access to healthcare services. Moreover, those data are at the basis of several research projects and publications [33], mostly in pharmacoepidemiology, health care management, and epidemiology, including studies on diseases with very low incidence [34].…”

Section: Italymentioning

confidence: 99%

Health Data for Public Health: Towards New Ways of Combining Data Sources to Support Research Efforts in Europe

Burgun¹,

Bernal-Delgado²,

Kuchinke³

et al. 2017

Yearb Med Inform

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Use of administrative data in healthcare research

Cited by 103 publications

References 28 publications

The effect of the look-back period for estimating incidence using administrative data

The effect of the look-back period for estimating incidence using administrative data

The incidence of collagen-associated adverse events in pediatric population with the use of fluoroquinolones: a nationwide cohort study in Taiwan

Health Data for Public Health: Towards New Ways of Combining Data Sources to Support Research Efforts in Europe

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