Use of Acticoat™ dressings in burns: What is the evidence?

Application of the Nanocrystalline Silver in Treatment of Burn Wounds in Children

“…Thus, the applied local agent is subjected to permanent control (both objective and subjective). The perfect dressing for children should provide optimal protection, reparation and minimization of the pain (Khundkar et al 2010). Silver-impregnated Acticoat™ dressing has been used in the Clini c o f B u r n s a t t h e "Pirogov" Emergency Hospital since 2004 and has gradually prevailed as the standard dressing in the treatment of burn wounds and post-traumatic defects.…”

Giant Omphalocele: What's the Way to Go?

“…ACTICOAT [42][43][44][45]), while allowing the baby to be fed soon after birth, whenever possible, with little stress in this extremely delicate period of life, not only for those children with prematurity or associated anomalies. During this time the baby can undergo all the necessary work-up to identify associated anomalies.…”

“…ACTICOAT has been extensively used in the management of burns. Low levels of serum silver and no haematological nor biochemical indicators of toxicity associated with the silver absorption have been reported in 2007 in a prospective study from Vlachou et al [43] and a more recent systematic review from Khundkar et al [44] showed that ACTICOAT has better antimicrobial activity, fewer adverse effects and reduces healing times compared to other available silver dressing. The use of ACTICOAT has been reported feasible and effective even in the management of neonatal burns, with very low serum silver levels and no systemic side effects [45].…”

Treatment of Chronic Wounds With the Silver-Containing Activated Carbon Fiber Dressing: Three Cases

“…Furthermore, the use of antibiotics would result in generation of drug-resistant bacteria, increasing the difficulty of wound care. Silver has been utilized as medication for more than 2,000 years [9,10]. The antimicrobial activity of silver ion is achieved via binding to bacterial proteins, causing alterations of their structure which in turn block protein synthesis, cellular respiratory, electron transport chain, and destroy bacterial cell membranes.…”