Use of a thrombin–gelatin haemostatic matrix in endoscopic endonasal extended approaches: technical note

Cappabianca, Paolo; Esposito, Felice; Esposito, Isabella; Cavallo, Luigi Maria; Leone, Carlo Antonio

doi:10.1007/s00701-008-0172-6

Cited by 51 publications

(22 citation statements)

References 20 publications

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“…There was only 1 pseudoaneurysm from the 9 cases treated with the muscle patch. In several case reports, FloSeal, a gelatin‐thrombin hemostatic matrix sealant, has been shown to be effective in endoscopic arterial major injury management when used as a focally applied, topical packing agent . This must be used with caution, however, because it has the ability to embolize into the parent vessel.…”

Section: Intraoperative Considerationsmentioning

confidence: 99%

“…There are no previously published systematic reviews, clinical guidelines, or RCTs pertaining to the use of nasal packing during endoscopic injury of a minor artery during ESBS. There are several case reports of the use of FloSeal as an effective agent in focally applied topical packing . In addition, Avitene packing with warm saline irrigation or Gelfoam packing has also been recommended for small arterial injuries …”

Section: Intraoperative Considerationsmentioning

confidence: 99%

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ICAR: endoscopic skull‐base surgery

Wang

Zanation

Gardner

et al. 2019

Int Forum Allergy Rhinol

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150

279

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Background Endoscopic skull‐base surgery (ESBS) is employed in the management of diverse skull‐base pathologies. Paralleling the increased utilization of ESBS, the literature in this field has expanded rapidly. However, the rarity of these diseases, the inherent challenges of surgical studies, and the continued learning curve in ESBS have resulted in significant variability in the quality of the literature. To consolidate and critically appraise the available literature, experts in skull‐base surgery have produced the International Consensus Statement on Endoscopic Skull‐Base Surgery (ICAR:ESBS). Methods Using previously described methodology, topics spanning the breadth of ESBS were identified and assigned a literature review, evidence‐based review or evidence‐based review with recommendations format. Subsequently, each topic was written and then reviewed by skull‐base surgeons in both neurosurgery and otolaryngology. Following this iterative review process, the ICAR:ESBS document was synthesized and reviewed by all authors for consensus. Results The ICAR:ESBS document addresses the role of ESBS in primary cerebrospinal fluid (CSF) rhinorrhea, intradural tumors, benign skull‐base and orbital pathology, sinonasal malignancies, and clival lesions. Additionally, specific challenges in ESBS including endoscopic reconstruction and complication management were evaluated. Conclusion A critical review of the literature in ESBS demonstrates at least the equivalency of ESBS with alternative approaches in pathologies such as CSF rhinorrhea and pituitary adenoma as well as improved reconstructive techniques in reducing CSF leaks. Evidence‐based recommendations are limited in other pathologies and these significant knowledge gaps call upon the skull‐base community to embrace these opportunities and collaboratively address these shortcomings.

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Section: Intraoperative Considerationsmentioning

confidence: 99%

Section: Intraoperative Considerationsmentioning

confidence: 99%

ICAR: endoscopic skull‐base surgery

Wang

Zanation

Gardner

et al. 2019

Int Forum Allergy Rhinol

Self Cite

150

279

View full text Add to dashboard Cite

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“…[11,12] Floseal can cause a hosttissue reaction and therefore carries theoretical risks, such as immunologically induced coagulopathy, IgEmediated anaphylaxis, infections and bovine spongiform encephalitis. [13] Fibrin glue does not adhere strongly to wet tissue, has little impact on active bleeding and carries a risk of infection. [14,15] In addition, use of fibrin glue is limited by the time required to obtain and prepare the product.…”

Section: Discussionmentioning

confidence: 99%

A new technique for management of intercavernous sinus bleeding with titanium clips in transsphenoidal surgery

et al. 2010

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“…8,11 A concern with gelatin hemostatic medications is the theoretical risks such as immunologically induced coagulopathy, IgE-mediated anaphylaxis, and the potential for thromboembolic complications. 2,7,9,12,13 Fibrin glue does not adhere strongly to wet tissue, needs a dry application surface to polymerize, and has little impact on active bleeding. In addition, the use of fibrin glue is limited by the time required to obtain and prepare the product.…”

Section: Discussionmentioning

confidence: 99%

Use of Tissue-Glue–Coated Collagen Sponge (TachoSil) to Repair Minor Cerebral Dural Venous Sinus Lacerations

Gazzeri

Galarza

Fiore

et al. 2015

Operative Neurosurgery

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Use of a thrombin–gelatin haemostatic matrix in endoscopic endonasal extended approaches: technical note

Abstract: The thrombin-gelatin matrix could represent a valuable tool when other haemostatic strategies are ineffective or suboptimal. It is safe and biocompatible when compared with haemostatic agents currently in use.

Cited by 51 publications

References 20 publications

ICAR: endoscopic skull‐base surgery

ICAR: endoscopic skull‐base surgery

A new technique for management of intercavernous sinus bleeding with titanium clips in transsphenoidal surgery

Use of Tissue-Glue–Coated Collagen Sponge (TachoSil) to Repair Minor Cerebral Dural Venous Sinus Lacerations

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