“…clomocycline) are under investigation (Oller, 1968), and also mixed preparations (Willcox, 1969) Doxycycline recently claimed to give 95 per cent. success with a single dose (Domescik, McLone, Scotti, and Mackey, 1969), as also methacycline (McLone, Billings, Lucas, Hardegree, and Hackney, 1968) Little used, but 90 to 96 per cent. cure rate reported with single oral doses (Greaves, Macdonald, Romansky, and Taggart, 1950;Tiedemann and others, 1962;Gjessing and Odegaard, 1967), and when combined with single injections of procaine penicillin (Gjessing and Odegaard, 1967) Its analogue, dextrosulphenidol, also effective (Table V) Analogue of chloramphenicol; methylsulphonyl group substituted for nitro group Less effective synthetic chloramphenicol-like substance Effective in multiple dosage (1-5 g. over one…”