Use of a Natural Compound Made of <i>Ecklonia bicyclis</i> Seaweed, <i>Tribulus terrestris</i> and Water-Soluble Chitosan Oligosaccharide, in Male Sexual Asthenia with Mild or Mild-Moderate Erectile Dysfunction and Serum Testosterone Levels at the Lower Limit of Normal

Abstract

Objectives: to evaluate the effectiveness of a natural compound made of Ecklonia bicyclis Seaweed, Tribulus terrestris and water-soluble chitosan oligosaccharide, in the male sexual asthenia with mild or mild-moderate erectile dysfunction and serum testosterone levels between 280 and 350 ng/dl. Materials and Methods: 84 male patients affected by reduced libido and serum testosterone levels at the lower limit of normal, were recruited. We have separated patients in three different age groups: group A (18-45 years), group B (45-59 years), group C (>60 years). All subjects answered the International index of erectile function questionnaire (IIEF-5) and underwent determination of serum total testosterone before and after 30 days of treatment. Results: Before treatment, the group A showed mean (± standard deviation) total testosterone 321.9 ± 19.2 ng/dl and mean IIEF-5 18.6 ± 1.97, in the group B it was 318.5 ± 18.1 ng/dl and 16.3 ± 2.66, and finally in the group C it was 305.4 ± 13.1 ng/dl and 14.2 ± 1.95 respectively. After treatment mean total testosterone and mean IIEF-5 were respectively: group A (448 ± 111.46 ng/dl and 21.84 ± 3.41); group B (453.8 ± 105.23 ng/dl and 20.4 ± 3.81

“Tradamixina TP” Compound in Monotherapy for Three Months in Patients with LUTS: Observational Study on Improvement of Urinary Symptoms and Sexual Function in Men

“…Besides, Tribulus terrestris has an effect on erectile function due to its ability to activate the neuronal NO synthase pathways that act at the endothelial level of the corpora cavernosa [20]. Some authors have reported that Tribulus terrestris also increases the serum levels of total testosterone [21]. However, evidence is not converging.…”

Efficacy Evaluation of Plant Products in the Treatment of Erectile Dysfunction Related to Diabetes

“…However, most plant compounds considered endowed by positive effects in the treatment of erectile dysfunction have been investigated only in vitro and/or in vivo models. Few plant compounds (e.g., Crocus sativus L. [21], Tribulus terrestris [22], Panax ginseng [23][24][25] have been tested in humans affected by this syndrome. Among these, the most investigated is P. ginseng, which has been evaluated either as a single agent [23,24] or in combination with M. oleifera and rutin [25] in clinical trials with promising results.…”