Whcri taken into the systemic circulation, 1 '~~~~ deposits predominantly ill the skeleton, where it may produce bone disease (including cancer) many years later. Its absorption rate from the gastrointestinal tract is only about 0.003 per rent. 12 small amount niay be absorbed through the intact skin and through contaminated cut3 and puncture xvounds. Absorption from the lung may be from I to 10 per cent of the inhaled dose, depending 011 particle size, solubility, chemical fornr, etc. Inhalation of contaminated air is potentially ihe most important mode of exposure, and its control is largely responsible for the rigorous closed-systems and other industrial hygiene arid engineering practices employed in plutonium