Use of 18 F-FDG PET/CT in the preoperative evaluation of patients diagnosed with peritoneal carcinomatosis of ovarian origin, candidates to cytoreduction and hipec. A pending issue

Specific Regions, Rather than the Entire Peritoneal Carcinosis Index, are Predictive of Complete Resection and Survival in Advanced Epithelial Ovarian Cancer

“…In particular, the sensitivity of CT and 18 F-FDG positron emission tomography/CT in regions 9 to 12 was disappointing, with sensitivities of merely 21% and 6%, respectively. 6 In a similar study of 25 patients with colorectal cancer, preoperative PCI evaluation with CT showed a significant interobserver difference for tumor size of 1 to 5 cm and sensitivity for detection of carcinosis on the small intestine and mesentery of 18% to 54%. 3 Because imaging has failed to predict the presence of nonresectable carcinosis on the small intestine and hepatoduodenal ligament, several studies have investigated the possibility to perform laparoscopic PCI.…”

Systematic review on the accuracy of positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging in the management of ovarian cancer: Is functional information really needed?

“…Of these, two studies used ce PET/CT for analysis[1223] and the rest of the studies used ld PET/CT for analysis. [242526272829]…”

“…Therefore, there were three studies[242527] and 184 patients that analyzed peritoneal carcinomatosis for staging of OCs and achieved pooled sensitivity of 86.78%. We were not able to calculate pooled specificity as we did not have information on the number of benign cases in one of the studies.…”

“…We were not able to calculate pooled specificity as we did not have information on the number of benign cases in one of the studies. [25]…”

Are positron emission tomography-computed tomography (PET-CT) scans useful in preoperative assessment of patients with peritoneal disease before cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)?

“…However, the sensitivity of these modalities can drop to as low as 9% [18] in low-volume peritoneal disease. Imaging scores have also been suggested to enhance patient selection, but these are often based on CT scans and have their limitations [19][20][21].…”