Use and abuse of retention indices in gas chromatography

Bizzo, Humberto R.; Brilhante, Nathália S.; Nolvachai, Yada; Marriott, Philip J.

doi:10.1016/j.chroma.2023.464376

Cited by 3 publications

(3 citation statements)

References 47 publications

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“…Though valuable, retention indices can lead to incorrect conclusions if misused or misinterpreted. 124,125 Errors in implementing and citing retention index values have resulted in questionable identifications in the scientific literature, emphasizing the need for a better understanding and correct application of retention indices. 124 To address the limitations of relying solely on RI, combining spectral similarity (SS) scores and RI scores provides complementary information and increases confidence in compound identification.…”

Section: Identificationmentioning

confidence: 99%

“…Though valuable, retention indices can lead to incorrect conclusions if misused or misinterpreted. , Errors in implementing and citing retention index values have resulted in questionable identifications in the scientific literature, emphasizing the need for a better understanding and correct application of retention indices …”

Section: Retention Indices and Their Relevance For Identificationmentioning

confidence: 99%

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Enhancing Odor Analysis with Gas Chromatography–Olfactometry (GC-O): Recent Breakthroughs and Challenges

Mahmoud,

Zhang

2024

J. Agric. Food Chem.

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Gas chromatography−olfactometry (GC-O) has made significant advancements in recent years, with breakthroughs in its applications and the identification of its limitations. This technology is widely used for analyzing complex odor patterns. The review begins by explaining the principles of GC-O, including sample preparation, separation methods, and olfactory evaluation techniques. It then explores the diverse range of applications where GC-O has found success, such as food and beverage industries, environmental monitoring, perfume and aroma development, and forensic analysis. One of the major breakthroughs in GC-O analysis is the improvement in separation power and resolution of odorants. Techniques like rapid GC, comprehensive twodimensional GC, and multidimensional GC have enhanced the identification and quantification of odor-active chemicals. However, GC-O also has limitations. These include the challenges in detecting and quantifying trace odorants, dealing with matrix effects, and ensuring the repeatability and consistency of results across laboratories. The review examines these limitations closely and discusses potential solutions and future directions for improvement in GC-O analysis. Overall, this review presents a comprehensive overview of the recent advances in GC-O, covering breakthroughs, applications, and limitations. It aims to promote the wider usage of GC-O analysis in odor analysis and related industries. Researchers, practitioners, and anyone interested in leveraging the capabilities of GC-O in analyzing complex odor patterns will find this review a valuable resource. The article highlights the potential of GC-O and encourages further research and development in the field.

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Section: Identificationmentioning

confidence: 99%

Section: Retention Indices and Their Relevance For Identificationmentioning

confidence: 99%

Enhancing Odor Analysis with Gas Chromatography–Olfactometry (GC-O): Recent Breakthroughs and Challenges

Mahmoud,

Zhang

2024

J. Agric. Food Chem.

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“…It has evolved into a standard procedure for researching the ingredients in natural drugs, and it is particularly one of the most significant and widely utilized tools for studying volatile chemicals. [23][24] For example, the composition analysis of petroleum ether extracts from Bidens Pilosa, Aconitum polycarpum, Azadiracta indica, and Cucurbita pepo; [25][26][27][28] methanolic extracts from Gardenia jaminoides, Hibiscus sabdariffa; [29][30] and the essential oils from Euphorbia larica, Piper mikanianum. [31][32] In this study, we utilized a cold-soaking method and assisted ultrasonic treatment to extract the petroleum ether extract of MC.…”

Section: Introductionmentioning

confidence: 99%

Inhibitory Activity Against Rhizoctonia Solani and Chemical Composition of Extract from Moutan Cortex

Zhao,

Wang,

Han

et al. 2024

Chemistry & Biodiversity

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Rice sheath blight (RSB), caused by Rhizoctonia solani, is a significant disease of rice. The negative effects of chemical fungicides have created an urgent need for low‐toxicity botanical fungicides. Our previous research revealed that the ethanol crude extract of Moutan Cortex (MC) exhibited superior antifungal activity against R. solani at 1000 μg/mL, resulting in 100% inhibition rate. And the antifungal properties were mainly found in the petroleum ether extract. However, the active ingredients of the extract are still unclear. In this study, gas chromatography‐mass spectrometry (GC‐MS) was utilised for the analysis of its chemical components. The mycelium growth rate method was utilized to detect the antifungal activity. The findings indicated that paeonol constituted the primary active component, with a content of more than 96%. Meanwhile, paeonol was the most important antifungal active ingredient, the antifungal activity of paeonol (EC50 = 44.83 μg/mL) was much higher than that of β‐sitosterol and ethyl propionate against R. solani. Observation under an optical microscope revealed that paeonol resulted in abnormal mycelial morphology. This study provided theoretical support for identifying monomer antifungal compounds and developing biological fungicides for R. solani.

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Chemical composition, antimicrobial activity, and antioxidant capacity of Micromeria flagellaris Baker and M. madagascariensis Baker: Two endemic species from Madagascar as sources of essential oils

Rakotofina,

Donno,

Tombozara

et al. 2024

Heliyon

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Use and abuse of retention indices in gas chromatography

Cited by 3 publications

References 47 publications

Enhancing Odor Analysis with Gas Chromatography–Olfactometry (GC-O): Recent Breakthroughs and Challenges

Enhancing Odor Analysis with Gas Chromatography–Olfactometry (GC-O): Recent Breakthroughs and Challenges

Inhibitory Activity Against Rhizoctonia Solani and Chemical Composition of Extract from Moutan Cortex

Chemical composition, antimicrobial activity, and antioxidant capacity of Micromeria flagellaris Baker and M. madagascariensis Baker: Two endemic species from Madagascar as sources of essential oils

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