Usability of low-dose spiral computed tomography in the early detection of lung and mediastinal tumors

Kasuga, Ikuma; Maezawa, Hiromi; Okuyama, Atsushi; Taira, Mika; Gamou, Sanae; Takahashi, Daisuke; Ohtsubo, Osamu; Takahashi, Motoichirou

doi:10.7143/jhep.44.575

Cited by 1 publication

(1 citation statement)

References 38 publications

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“…[ 7 ] In fact, our previous study demonstrated that CR did not contribute to the early detection of lung cancer at health checkups. [ 8 ] In addition, a recent randomized controlled trial on lung cancer screening by CR did not show a reduction in mortality compared with that following usual care. [ 9 ] This means that CR may not contribute to the early detection of lung cancer and may not be a useful modality for lung cancer screening.…”

Section: Introductionmentioning

confidence: 99%

Which is a real valuable screening tool for lung cancer and measure thoracic diseases, chest radiography or low-dose computed tomography?: A review on the current status of Japan and other countries

Kasuga,

Yokoe,

Gamo

et al. 2024

Medicine

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Chest radiography (CR) has been used as a screening tool for lung cancer and the use of low-dose computed tomography (LDCT) is not recommended in Japan. We need to reconsider whether CR really contributes to the early detection of lung cancer. In addition, we have not well discussed about other major thoracic disease detection by CR and LDCT compared with lung cancer despite of its high frequency. We review the usefulness of CR and LDCT as veridical screening tools for lung cancer and other thoracic diseases. In the case of lung cancer, many studies showed that LDCT has capability of early detection and improving outcomes compared with CR. Recent large randomized trial also supports former results. In the case of chronic obstructive pulmonary disease (COPD), LDCT contributes to early detection and leads to the implementation of smoking cessation treatments. In the case of pulmonary infections, LDCT can reveal tiny inflammatory changes that are not observed on CR, though many of these cases improve spontaneously. Therefore, LDCT screening for pulmonary infections may be less useful. CR screening is more suitable for the detection of pulmonary infections. In the case of cardiovascular disease (CVD), CR may be a better screening tool for detecting cardiomegaly, whereas LDCT may be a more useful tool for detecting vascular changes. Therefore, the current status of thoracic disease screening is that LDCT may be a better screening tool for detecting lung cancer, COPD, and vascular changes. CR may be a suitable screening tool for pulmonary infections and cardiomegaly.

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Section: Introductionmentioning

confidence: 99%