US Renal Data System 2012 Annual Data Report

Collins, Allan J.; Foley, Robert N.; Herzog, Charles A.; Chavers, Blanche M.; Gilbertson, David T.; Ishani, Areef; Johansen, Kirsten L.; Kasiske, Bertram L.; Kutner, Nancy G.; Liu, Jiannong; Peter, Wendy L. St.; Ding, Shilei; Guo, Haifeng; Kats, Allyson M; Lamb, Kenneth; Li, Shuling; Li, Suying; Roberts, Tricia; Skeans, M. A.; Snyder, Jon J.; Solid, Craig A.; Thompson, Bryn; Weinhandl, Eric D.; Xiong, Hui; Yusuf, Akeem; Zaun, David; Arko, Cheryl; Chen, Shu‐Cheng; Daniels, Frank; Ebben, James; Frazier, Eric; Hanzlik, Christopher; Johnson, Roger N.; Sheets, Daniel; Wang, Xinyue; Forrest, Beth; Constantini, Edward; Everson, Susan; Eggers, Paul W.; Agodoa, Lawrence Y.

doi:10.1053/j.ajkd.2012.11.031

Cited by 309 publications

(247 citation statements)

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“…That is an average of 66 patients in each treatment center (5). In United States of America in 2010, there were 594,374 cases with end stage renal disease, of whom, 415,013 patients were on dialysis (6). The number of hemodialysis patients in Iran is annually increased by 15% (7).…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Duration of Dialysis and Quality of Life in Hemodialysis Patients

Barzegar

Jafari

Charati

et al. 2017

Iran J Psychiatry Behav Sci

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Background: The number of patients with chronic renal failure is increasing in Iran. Quality of life is an important indicator that reveals the sense of well-being, positive understanding of their, and the effectiveness of health care in patients undergoing dialysis, which could be affected by duration of dialysis. Objectives: This study aimed at investigating the relationship between quality of life and duration of dialysis in hemodialysis patients. Methods: In this descriptive correlational study, 246 patients with chronic kidney failure were selected by Single-stage stratified cluster sampling. Hemodialysis patients were put into 2 groups with a duration of hemodialysis less than and more than 36 months and were then compared with each other. The quality of life was measured using the kidney disease quality of life short form (KDQOL-SF36). Data analysis was performed by the Pearson correlation coefficient, independent t-test, and ANOVA Results: The mean duration of hemodialysis patients was 34.03 months. There was no significant relationship between the quality of life in patients and duration of hemodialysis. Poor quality of life had a significant correlation with old age (P < 0.001), educational level (P < 0.001), job, and income (P < 0.001). Conclusions:The findings showed poor quality of life in patients on dialysis. The length of the disease and other accompanying diseases reduced the quality of life in dialysis patients as their age increased. It is evident that educated people who have better access to sources of support and are able to cope with disease complications have a higher quality of life.

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Section: Introductionmentioning

confidence: 99%

Relationship Between Duration of Dialysis and Quality of Life in Hemodialysis Patients

Barzegar

Jafari

Charati

et al. 2017

Iran J Psychiatry Behav Sci

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“…Egy évtizedekkel ezelőtt induló és hosszan tartó dialízisterápia hatásait vizsgáló tanulmányban, ahol a résztvevők átlagosan 16 éve álltak dialí-ziskezelés alatt, a nyomon követett betegek 92%-ánál diagnosztizáltak vascularis kalcifi kációt [5]. Az USRDS (United States Renal Data System) adatai szerint 2010-ben az Egyesült Államokban a normálpopulációhoz ké-pest a krónikus vesebetegek körében 59%-kal magasabb a cardiovascularis eseményekkel összefüggő halálozási kockázat [6]. Ma Magyarországon minden tizedik ember érintett valamely vesebetegségben, évente közel 6500, krónikus veseelégtelenségben szenvedő beteg életben maradását biztosítja a művesekezelés a Magyar Nephrologiai Társaság adatai szerint.…”

Section: Vascularis Kalcifi Káció Vesebetegekbenunclassified

Az oxidatív stressz hozzájárul a krónikus vesebetegeket érintő vascularis kalcifikáció kialakulásához

Nyitrai

Balla

2015

Orvosi Hetilap

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A rendszeres dialíziskezelésre szoruló vesebetegek körében a halálozási ok leggyakrabban valamilyen cardiovascularis megbetegedés. A cardiovascularis események egyik előidézője a vascularis kalcifi káció, amelynek kialakulási esélye a krónikus vesebetegek körében extrém magas. A kalcifi káció nemcsak az évtizedek óta dialízisterápiában részesülő idősebb korosztályban jelentkezik, hanem a fi atal korosztályt is érinti. Az érrendszerben megjelenő masszív, nagy kiterjedésű kalcifi káció aktív, jól szabályozott komplex folyamat eredményeként alakul ki. Előidézői között szerepel az oxidatív stressz, amely a beteg szervezetében a vese működési zavara következtében nagymértékben fokozódik. A megemelkedett oxidatív terhelést tovább fokozzák a képződő oxidált LDL-formák, amelyek előidézői az endothelialis diszfunkciónak és az érben található simaizomsejtek csontszerű sejtté történő transzdifferenciációjának. Az oxidált hemoglobinból kiszabaduló szabad hem is képes az LDL oxidációjára és ezzel hozzájárul az atherosclerosis kialakulásához. A hemoxigenáz-1/ferritin rendszer indukciója mérsékli a szabad hem ezen káros hatásait. Orv. Hetil., 2015Hetil., , 156(47), 1926Hetil., -1931 Kulcsszavak: vascularis kalcifi káció, krónikus veseelégtelenség, oxidatív stressz, oxidált LDL Oxidative stress: one of the major causes of vascular calcifi cation in chronic kidney disease patientsThe leading cause of high mortality in dialyzed patients is cardiovascular disease. One of the main contributors of cardiovascular event is vascular calcifi cation, which occurs even in very young patients. Multiple factors and complex mechanisms are involved in the formation of robust vascular calcifi cation which affects a large vascular area observed in chronic kidney diseases. Patients on dialysis are exposed to enhanced oxidative stress as a result of increased prooxidant activity and reduced anti-oxidant systems. The oxidation of lipoprotein particles is implicated in the development of vascular damage representing oxidative threat, which leads to endothelial dysfunction. Moreover, in a prooxidant environment osteoblastic trans-differentiation of smooth muscle cells was shown to occur. Heme derived from oxidized hemoglobin might contribute to the formation of reactive lipid metabolites. This oxidative burden contributes to the development of atherosclerosis and vascular calcifi cation. Heme oxygenase-1 and ferritin may serve as intracellular defense mechanisms against such an insult.Keywords: vascular calcifi cation, renal insuffi ciency, oxidative stress, oxidized LDL Nyitrai, M., Balla, Gy., Balla, J. [Oxidative stress: one of the major causes of vascular calcifi cation in chronic kidney disease patients].

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“…The number of patients with end stage kidney disease (ESKD) receiving dialysis treatment is increasing worldwide including United Arab Emirates (UAE) [1,2]. UAE recently expand its national dialysis service to meet the demand of increasing prevalence of chronic kidney diseases (CKDs).…”

Section: Introductionmentioning

confidence: 99%

Provision of renal care for patients with end stage kidney disease in persistent vegetative state, in United Arab Emirates: a national survey of renal physicians

Alshamsi

Chaaban

Alrukhaimi

et al. 2018

Libyan Journal of Medicine

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Patients with end stage kidney disease (ESKD) with severely impaired cognitive function have no survival benefit from dialysis. We therefore undertook a survey to explore the renal physicians’ practices of withholding and withdrawal of dialysis treatment in vegetative state patients in the United Arab Emirates (UAE). A cross sectional survey of 29 nephrology practices in UAE exploring physicians’ practices in making decisions of withholding and withdrawal of dialysis treatment during provision end-of-life care for patients in persistent vegetative state (PVS).The majority of participants practice in governmental non-for-profit dialysis units (79%), and think they are well prepared to make decision with patients and family on issues of dialysis withdrawal and withholding (69%). If a chronic dialysis patient became permanently unconscious only few respondents (17%) indicated probability of stopping dialysis. On the other hand, more respondents (48%) reported that dialysis is likely to be withheld in PVS patients who develop kidney failure. In high risk or poor prognosis ESKD patients and given how likely they would consider each option independently, respondents reported they are likely to consider time-limited dialysis in 78% of the time followed by stopping (46%) or forgoing (27%) dialysis. Majority of the participants perceived that their decisions in providing renal care for PVS patients in UAE were influenced by the family sociocultural beliefs (76% of participants), the current hospital policies (72% of participants), and by Islamic beliefs (66% of participants). Only few perceived access to palliative care (30%) and treatment cost (17%) to have an impact on their decision making.Decisions of initiation and continuation of dialysis treatment to ESKD patients in PVS are prevalent among nephrology practices in UAE. Development of local guidelines based on the societal values along with early integration of palliative kidney failure management care would be required to improve the quality of provision of end-of-life renal care in UAE.Abbreviations: ESKD: stage kidney disease; UAE: United Arab Emirates; PVS: persistent vegetative state; RPA: Renal Physicians Association; ASN: American Society of Nephrology; EMAN: Emirates Medical Association Nephrology Society; CPR: cardiopulmonary resuscitation.

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US Renal Data System 2012 Annual Data Report

Cited by 309 publications

References 0 publications

Relationship Between Duration of Dialysis and Quality of Life in Hemodialysis Patients

Relationship Between Duration of Dialysis and Quality of Life in Hemodialysis Patients

Az oxidatív stressz hozzájárul a krónikus vesebetegeket érintő vascularis kalcifikáció kialakulásához

Provision of renal care for patients with end stage kidney disease in persistent vegetative state, in United Arab Emirates: a national survey of renal physicians

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