US Characterization of Ovarian Masses: A Meta-Analysis

Kinkel, Karen; Hricak, Hedvig; Lu, Ying; Tsuda, Kazuki; Filly, Roy A.

doi:10.1148/radiology.217.3.r00dc20803

Cited by 194 publications

(112 citation statements)

References 53 publications

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“…Ultrasound has been largely used in the differential diagnosis of adnexal masses and its diagnostic value is well-established. 5 Most studies assessing the role of ultrasound for surgical or referral triaging of adnexal masses have been performed in series in which clinical complaints were not taking into account. [15][16][17][18][19] It could be speculated that the performance of this diagnostic technique could be different in women complaining symptoms suggestive of ovarian cancer.…”

Section: Discussionmentioning

confidence: 99%

“…5 Due to this fact, ultrasound is considered as the first step imaging technique to be used when assessing an adnexal mass. 6 In 2003 we published our ultrasound scoring system, based on a morphologic and Doppler assessment, for distinguishing between benign and malignant adnexal masses 7 which has been shown to be useful in asymptomatic patients.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of an Ultrasound-based Scoring System for Triaging Ovarian Tumors in Symptomatic Women

Galván¹,

Alcázar

Royo³

et al. 2009

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Objective: To evaluate prospectively an ultrasound-based scoring system as a method for triaging symptomatic women presenting with an adnexal mass for surgical treatment.Methods: 151 symptomatic women scheduled for surgical treatment at our institution were included in this prospective study. Patients were evaluated by transvaginal power Doppler ultrasound prior to surgery. Patients were classified as low-risk or high-risk for malignancy according an ultrasound-based scoring system. Patients with low risk for malignancy were scheduled for laparoscopy and patients for high risk for malignancy were scheduled for laparotomy. Some patients with high-risk were scheduled for advanced oncologic laparoscopic surgery. Patients with low risk but tumor size > 10 cm were scheduled for laparotomy.Results: 82 women presented with pelvic pain, 8 had uterine bleeding and 61 referred symptoms suggestive for ovarian malignancy, such as abdominal swelling, bloating and abdominal discomfort. 75 (49.7%) masses were considered as "low-risk" and treated by laparoscopy in 58 cases and by laparotomy in 7 cases, because emergency or associated pathology (All tumors were benign). 76 (50.3%) masses were considered as "high-risk" and all treated by laparotomy (56 malignant and 4 benign tumors) or by advanced laparoscopy (16 malignant tumors). Ten (6.7%) tumors were considered as "low-risk" but scheduled for primary laparotomy because of size > 10 cm (9 benign and 1 malignant). Sensitivity, specificity, PPV and NPV for this scoring system were 98.6%, 94.9%, 94.7% and 98.7%, respectively. The scoring system were more sensitive than patient's complaints (98.6% vs 79.5%, p < 0.0001) and more specific than physical examination (94.9% vs 85.9%, p < 0.0001) Conclusions: Ultrasound based triage of symptomatic women diagnosed, as having an adnexal mass is effective for selecting surgical approach.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Assessment of an Ultrasound-based Scoring System for Triaging Ovarian Tumors in Symptomatic Women

Galván¹,

Alcázar

Royo³

et al. 2009

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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“…Therefore, the preoperative assessment of the adnexal mass by ultrasonography would include the size, consistency and blood flow to determine the likelihood of malignancy. [6][7][8] …”

Section: Angiogenesis In Borderline Tumorsmentioning

confidence: 99%

Doppler Evaluation of the Ovary: Clinical Applications and Challenges

Žalud¹

2008

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Abstract:Transvaginal sonography has been shown to be an accurate technique for discriminating between benign and malignant adnexal masses. Accurate preoperative differential diagnosis of adnexal masses is essential for optimizing patients' treatment. The advancement and wider availability of therapies of assisted conception have occurred to a large extent as a result of developments in ultrasonography. Transvaginal color Doppler has opened up exciting new possibilities for the better understanding of the physiology and pathophysiology of ovarian blood flow, resulting in a number of completely new diagnostic parameters.

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“…Существующие методы диагностики РЯ, утвер-жденные Обществом онкологов-гинекологов (Society of Gynecologic Oncology -SGO) и Американской кол-легией акушеров и гинекологов (American College of Obstetricians and Gynecologyst -ACOG), включают клинический осмотр с подробным сбором анамнеза и оценкой симптомов, лучевые методы визуализации (трансвагинальный ультразвук, ультразвуковую допле-рографию, компьютерную томографию (КТ), магнит-но-резонансную томографию (МРТ) и позитронно-эмиссионную томографию (ПЭТ)), генетическое консультирование женщин с высоким риском разви-тия заболевания и определение биомаркеров различ-ными методами, основанными как на определении экспрессии белков, так и на определении изменений генов [9,[12][13][14][15].…”

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