Urticarial Vasculitis Treated With Colchicine

Wiles, John C.; Hansen, Ronald C.; Lynch, Peter

doi:10.1001/archderm.1985.01660060116035

Cited by 44 publications

(11 citation statements)

References 13 publications

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“…CU patients with neutrophilic inflammation responded to colchicine,[138] and case reports suggest its efficacy in patients with urticarial vasculitis [139-141]. Colchicine is generally well-tolerated with the most frequent adverse effect being diarrhea.…”

Section: Treatmentmentioning

confidence: 99%

Diagnosis and Treatment of Urticaria and Angioedema: A Worldwide Perspective

Sánchez‐Borges

Asero

Ansotegui³

et al. 2012

World Allergy Organization Journal

180

111

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Urticaria and angioedema are common clinical conditions representing a major concern for physicians and patients alike. The World Allergy Organization (WAO), recognizing the importance of these diseases, has contributed to previous guidelines for the diagnosis and management of urticaria. The Scientific and Clinical Issues Council of WAO proposed the development of this global Position Paper to further enhance the clinical management of these disorders through the participation of renowned experts from all WAO regions of the world. Sections on definition and classification, prevalence, etiology and pathogenesis, diagnosis, treatment, and prognosis are based on the best scientific evidence presently available. Additional sections devoted to urticaria and angioedema in children and pregnant women, quality of life and patient-reported outcomes, and physical urticarias have been incorporated into this document. It is expected that this article will supplement recent international guidelines with the contribution of an expert panel designated by the WAO, increasing awareness of the importance of urticaria and angioedema in medical practice and will become a useful source of information for optimum patient management worldwide.

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Section: Treatmentmentioning

confidence: 99%

Diagnosis and Treatment of Urticaria and Angioedema: A Worldwide Perspective

Sánchez‐Borges

Asero

Ansotegui³

et al. 2012

World Allergy Organization Journal

180

111

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“…[5][6][7] Because hypocomplementaemic urticarial vasculitis often requires long-term application of high doses of corticosteroids, the well-known side-effects of such chronic treatment occur quite often. systemic lupus erythematosus, viral hepatitis or other viral infections, monoclonal gammopathies and the use of certain drugs.…”

Section: Discussionmentioning

confidence: 99%

Hypocomplementaemic urticarial vasculitis: successful treatment with cyclophosphamide-dexamethasone pulse therapy

Worm

Muche

Schulze

et al. 1998

British Journal of Dermatology

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Systemic hypocomplementaemic urticarial vasculitis unresponsive to several immunosuppressive and immunomodulatory drugs was seen in two women aged 43 and 45 years. Cyclophosphamide-dexamethasone pulse therapy was started in both patients and resulted in significant clinical improvement. The pulse treatment was well tolerated in both patients and no major adverse effects occurred. These cases indicate that cyclophosphamide-dexamethasone pulse therapy is efficient in the treatment of hypocomplementaemic urticarial vasculitis.

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“…En casos refractarios es necesario utilizar esteroides sistémicos. 3,14 La urticaria vasculítica responde bien a la dapsona (100 mg al día), 50 colchicina (0.6 mg dos o tres veces al día) 51 e hidroxicloroquina (200 mg dos veces al día). 52 En hipersensibilidad a AINE, el objetivo principal es proporcionar al paciente una opción analgésica, antipirética y antiinflamatoria segura; la confirmación debe realizarse por medio de una provocación oral bajo condiciones controladas.…”

Section: Tratamientounclassified

Angioedema

Holguín-Gómez

Vásquez-Ochoa

Cardona

2016

RAM

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Angioedema is defined as edema of the skin or mucosa, including the respiratory and the gastrointestinal mucosa, which is self-limiting, and in most cases is completely resolved in less than 72 hours. It occurs due to increased permeability of the mucosal and submucosal capillaries and postcapillary venules, with resulting plasma extravasation. There are different types of angioedema: histaminergic (which may be mediated by immunoglobulin E), hereditary, from acquired C1 inhibitor deficiency, from angiotensin converting enzyme inhibitor, bradykinin-mediated, and nonhistaminergic idiopathic angioedema. Treatment depends on the cause of angioedema, age, and the frequency and severity of manifestations. The main measures are avoiding external triggers or causes, giving antihistamines, steroids, or adrenaline for histaminergic angioedema; replacing the deficient protein or blocking the action of bradykinin in C1 inhibitor deficiency and angioedema from angiotensin converting enzyme inhibitor.

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Urticarial Vasculitis Treated With Colchicine

Cited by 44 publications

References 13 publications

Diagnosis and Treatment of Urticaria and Angioedema: A Worldwide Perspective

Diagnosis and Treatment of Urticaria and Angioedema: A Worldwide Perspective

Hypocomplementaemic urticarial vasculitis: successful treatment with cyclophosphamide-dexamethasone pulse therapy

Angioedema

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