Urticaria and Mastocytosis

Grattan, Frcp Consultant Dermatologist C. E. H.; Black, Frcp Honorary Senior A. Kobza

doi:10.1002/9781444317633.ch22

Cited by 4 publications

(1 citation statement)

References 278 publications

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“…The cutaneous forms of mastocytoses include urticaria pigmentosa, diffuse cutaneous mastocytosis, maculopapular mastocytosis, mastocytoma and telangiectasia macularis eruptiva perstans (TMEP). 1-6 TMEP is a rare disease, found in less than 1% of patients with cutaneous mastocytosis. It affects predominantly adults and is characterized by erythematous and/ or yellow-brownish macules with telangiectasias, preferably located on the trunk and upper limbs.…”

Section: Introductionmentioning

confidence: 99%

Dermatoscopic findings in telangiectasia macularis eruptiva perstans

Unterstell

Lavorato

Nery

et al. 2013

An. Bras. Dermatol.

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Section: Introductionmentioning

confidence: 99%

Dermatoscopic findings in telangiectasia macularis eruptiva perstans

Unterstell

Lavorato

Nery

et al. 2013

An. Bras. Dermatol.

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Glove‐related hand urticaria caused by disposable gloves in healthcare workers

2014

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Platelet Count and IgE Level in Chronic Idiopathic Urticaria: A Case-control Study

Kalmarzi

Ahmadiniaz

Ataee

et al. 2022

RAIAD

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Background and Aim: Chronic Urticaria is an allergic disorder that affects about 0.5 to 5% of the population in different communities. The disease's chronic course and long-term onset impose high economic and psychological costs on communities, adversely affecting individual and social life. Platelets play a role in various pathophysiological processes, including inflammation and immunology. Growing evidence suggests that platelets are actively involved in the pathogenesis of various inflammatory disorders, including inflammatory skin diseases. This study investigated the relationship between platelet and Immunoglobulin-E markers and chronic idiopathic urticaria. Materials and Methods: In the present case-control study, for the study population, patients with chronic idiopathic urticaria were referred to the Asthma and Allergy Clinic, and their caregivers were selected as the case and control groups, respectively. In this study, the mean platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and Total IgE values were simultaneously measured in the case and control groups. After taking 5CCs of venous blood, a blood sample was sent to the laboratory for platelet and IgE marker measurements. Results: 100 patients and 100 healthy persons were studied in this study. The mean age in the case group was 34.95, and in the control group was 35.78 years. The results showed that the mean values of PLT, MPV, PDW, and Total IgE in the case group were 12.86, 9.83, 252190, and 147.05, respectively. The mean values of PLT, MPV, PDW, and Total IgE in the control group were 16.93, 7.53, 231410, and 15.29, respectively, which was statistically significant (P = 0.001). Moreover, Total IgE in the Autologous Serum Skin Test (ASST) positive group was higher than ASST negative group and was statistically significant (P = 0.001). Conclusion: The study results indicate the possible role of platelets in urticaria and inflammation. MPV in patients with chronic urticaria was higher than in the control group. The present study showed no significant relationship between the severity of urticaria and platelet markers, but there was a significant relationship between the severity of urticaria and ASST. Moreover, the severity of urticaria was higher in the positive skin test group.

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Urticaria and Mastocytosis

Cited by 4 publications

References 278 publications

Dermatoscopic findings in telangiectasia macularis eruptiva perstans

Dermatoscopic findings in telangiectasia macularis eruptiva perstans

Glove‐related hand urticaria caused by disposable gloves in healthcare workers

Platelet Count and IgE Level in Chronic Idiopathic Urticaria: A Case-control Study

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