Nowadays, nutraceuticals are being incorporated into
functional
foods or used as supplements with nonpharmacological approaches in
the prevention and management of several illnesses, including age-related
conditions and chronic neurodegenerative diseases. Nutraceuticals
are apt for preventing and treating such disorders because of their
nontoxic, non-habit-forming, and efficient bioactivities for promoting
neurological well-being due to their ability to influence cellular
processes such as neurogenesis, synaptogenesis, synaptic transmission,
neuro-inflammation, oxidative stress, cell death modulation, and neuronal
survival. The capacity of nutraceuticals to modify all of these processes
reveals the potential to develop food-based strategies to aid brain
development and enhance brain function, prevent and ameliorate neurodegeneration,
and possibly reverse the cognitive impairment observed in Alzheimer’s
disease, the most predominant form of dementia in the elderly. The
current review summarizes the experimental evidence of the neuroprotective
capacity of nutraceuticals against Alzheimer’s disease, describing
their mechanisms of action and the in vitro and in vivo models applied to evaluate their neuroprotective
potential.