Urothelial Tumors of the Upper Urinary Tract and Ureter

Sagalowsky, Arthur I.; Jarrett, Thomas W.; Flanigan, Robert C.

doi:10.1016/b978-1-4160-6911-9.00053-0

Cited by 22 publications

(23 citation statements)

References 308 publications

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“…This conservative approach has been applied in selected cases when nephron sparing for preservation of renal function is needed, such as in patients with a solitary kidney or with simultaneous bilateral tumors. 3 We present our experiences in performing percutaneous treatments in one such patient with a complex, high-grade UTUC in a solitary kidney.…”

Section: Introductionmentioning

confidence: 99%

“Extreme” Renal Preservation: Neoadjuvant Chemotherapy and Percutaneous Resection for Upper-Tract Urothelial Carcinoma in a Patient with Solitary Kidney—A Case Report

Williams

Atalla

Ghavamian³

et al. 2013

Journal of Endourology

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Section: Introductionmentioning

confidence: 99%

“Extreme” Renal Preservation: Neoadjuvant Chemotherapy and Percutaneous Resection for Upper-Tract Urothelial Carcinoma in a Patient with Solitary Kidney—A Case Report

Williams

Atalla

Ghavamian³

et al. 2013

Journal of Endourology

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“…Age at diagnosis has increased over time with a peak incidence now occurring between ages 75 and 79 [ 24 ]. As a result, more patients undergoing nephroureterectomy will likely develop chronic renal insuffi ciency, placing them at increased risk of all-cause mortality and cardiovascular events [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Surveillance After Treatment for Upper Tract Transitional Cell Carcinoma

Conlin

Duty

2015

Upper Urinary Tract Urothelial Carcinoma

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“…Open nephroureterectomy was performed based on a procedure previously described with a retroperitoneal approach (14). Some patients underwent laparoscopic nephroureterectomy, but the excision of the bladder cuff was performed by open procedure with a small incision.…”

Section: Surgery Regional Lymph Nodes and Lymphadenectomymentioning

confidence: 99%

Possible Role of Template-based Lymphadenectomy in Reducing the Risk of Regional Node Recurrence after Nephroureterectomy in Patients with Renal Pelvic Cancer

Kondo

Hara

Takagi

et al. 2014

Japanese Journal of Clinical Oncology

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Objective: It remains unclear whether lymphadenectomy alters regional node recurrence after nephroureterectomy in patients with urothelial carcinoma of the renal pelvis. The predictive factors for regional node recurrence are still unclear. In this study, we retrospectively examined how the extent of lymphadenectomy influences regional node recurrence in patients with urothelial carcinoma of the renal pelvis. Methods: From January 1988 through July 2013, we performed nephroureterectomy in 180 patients with non-metastatic (cN0M0) urothelial carcinoma of the renal pelvis at two Japanese institutes. Regional nodes were determined according to our previous mapping study: complete lymphadenectomy designates that all regional sites were dissected; incomplete lymphadenectomy that all sites were not dissected. A third group included those without lymphadenectomy. Results:The 5-year cancer-specific and recurrence-free survival was significantly higher in the complete lymphadenectomy group than in the incomplete lymphadenectomy or without lymphadenectomy groups (P ¼ 0.03). The incidence of regional node recurrence was significantly lower in the complete lymphadenectomy group at 2.9% (2/67) than in the incomplete lymphadenectomy at 18.1% (4/22) or without lymphadenectomy at 10.9% (10/91) groups (P ¼ 0.03). In patients with incomplete lymphadenectomy, 75% of regional node recurrence occurred outside of the dissected sites. Complete lymphadenectomy is shown to be a likely predictive factor of reduced risk of recurrence at the regional nodes by multivariate analysis, after adjusting for patient age, pathological T stage, and pathological nodal metastases. Conclusions: This study shows that template-based lymphadenectomy reduced the risk of regional node recurrence in patients with urothelial carcinoma of the renal pelvis and appears to result in improved survival.

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Urothelial Tumors of the Upper Urinary Tract and Ureter

Cited by 22 publications

References 308 publications

“Extreme” Renal Preservation: Neoadjuvant Chemotherapy and Percutaneous Resection for Upper-Tract Urothelial Carcinoma in a Patient with Solitary Kidney—A Case Report

“Extreme” Renal Preservation: Neoadjuvant Chemotherapy and Percutaneous Resection for Upper-Tract Urothelial Carcinoma in a Patient with Solitary Kidney—A Case Report

Surveillance After Treatment for Upper Tract Transitional Cell Carcinoma

Possible Role of Template-based Lymphadenectomy in Reducing the Risk of Regional Node Recurrence after Nephroureterectomy in Patients with Renal Pelvic Cancer

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