Urothelial Tumors: Moving from Morphology to Biology

Abstract

The fourth most common tumour of bladder is urothelial carcinoma. A great insight into the biology of the disease through molecular profiling and pathways analysis has been provided through the intense research involving the different molecular aspects of bladder cancer. Throughout this minireview, the general concepts of the molecular features of urothelial cancer will be reviewed. In addition, molecular-based classification for bladder carcinomas will be highlighted.