Uropathogenic Escherichia coli infection: innate immune disorder, bladder damage, and Tailin Fang II
Zong-ping Li,
Jun Li,
Tong-lu Li
et al.
Abstract:BackgroundUropathogenic Escherichia coli (UPEC) activates innate immune response upon invading the urinary tract, whereas UPEC can also enter bladder epithelial cells (BECs) through interactions with fusiform vesicles on cell surfaces and subsequently escape from the vesicles into the cytoplasm to establish intracellular bacterial communities, finally evading the host immune system and leading to recurrent urinary tract infection (RUTI). Tailin Fang II (TLF-II) is a Chinese herbal formulation composed of botan… Show more
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