Urologic Pathology

Borchert, Alex; Rogers, Craig G.

doi:10.1016/j.path.2018.07.012

Cited by 3 publications

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinically, initial diagnosis and treatment decisions for kidney cancer, are often made without histopathological information, based primarily on imaging, and surgical treatment [11]. Surgical procedures include radical nephrectomy and partial nephrectomy [12], but given the high invasiveness of CDC, radical nephrectomy is recommended and may be the only curable opportunity for CDC patients [13,14].…”

Section: Discussionmentioning

confidence: 99%

Collecting duct carcinoma with retroperitoneal mass as initial presentation: A rare case report

Liao

Xia

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Collecting duct carcinoma (CDC) is a rare renal tumor, originating from the distal collecting duct. CDC rarely presents as a primary tumor outside the renal system. Case presentation: In this study, we report a rare case of collecting duct carcinoma, with an initial presentation of retroperitoneal lymph node metastasis, and no identifiable primary renal tumor on CT, at the time of diagnosis. The patient was a 64-year-old man presenting with lower back pain. Preoperative CT showed a round, soft tissue mass, measuring 6.7×4.4×3.3 cm, in the left retroperitoneum with no exact occupying lesion in the left kidney. Clinically, ectopic pheochromocytoma was considered to be a differential diagnosis, and tumor resection was performed. Postoperative pathological results demonstrated that the mass was a fused lymph node, and the tumor cells were destroying the structure. The final diagnosis was lymph node metastatic collecting duct carcinoma, by histology and immunohistochemistry. No further treatment was performed as no space occupying lesion was found in the kidney. Three months later, CT was reexamined, and a mass of 3.6 cm in diameter, was found in the lower left kidney, along with multiple soft tissue masses, in the left renal hilum. Considering recurrence or metastasis, the patient was recommended to undergo surgical treatment, but the patient refused. Four months later, CT was re-examined. The tumor had rapidly progressed but the patient refused treatment again. As per the author's press release (eleven months after the first discovery), the patient is still alive. Conclusion: CDC is a rare malignant renal carcinoma, with a high chance of rapid progress, regional lymph nodes involvement and metastasis. It presents diagnostic challenges to clinicians and pathologists, particularly, in the absence of radiographically detectable intrarenal lesions. Definite diagnosis is based on pathological examination combined with immunohistochemical staining.

show abstract

Section: Discussionmentioning

confidence: 99%

Collecting duct carcinoma with retroperitoneal mass as initial presentation: A rare case report

Liao

Xia

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“Collecting duct carcinoma of the kidney: diagnosis and implications for management”

Cabanillas¹,

Montoya-Cerrillo²,

Kryvenko

et al. 2022

Urologic Oncology: Seminars and Original Investigations

View full text Add to dashboard Cite

Collecting duct carcinoma with retroperitoneal mass as initial presentation: a rare case report

Liao

Xia

et al. 2023

BMC Urol

View full text Add to dashboard Cite

Background Collecting duct carcinoma (CDC) is a rare renal tumor, originating from the distal collecting duct. CDC rarely presents as a primary tumor outside the renal system. Case presentation In this study, we report a rare case of collecting duct carcinoma, with an initial presentation of retroperitoneal lymph node metastasis, and no identifiable primary renal tumor on CT, at the time of diagnosis. The patient was a 64-year-old man presenting with lower back pain. Preoperative CT showed a round, soft tissue mass, measuring 6.7 × 4.4 × 3.3 cm, in the left retroperitoneum with no exact occupying lesion in the left kidney. Clinically, ectopic pheochromocytoma was considered to be a differential diagnosis, and tumor resection was performed. Postoperative pathological results demonstrated that the mass was a fused lymph node, and the tumor cells were destroying the structure. The final diagnosis was lymph node metastatic collecting duct carcinoma, by histology and immunohistochemistry. No further treatment was performed as no space occupying lesion was found in the kidney. Three months later, CT was reexamined, and a mass of 3.6 cm in diameter, was found in the lower left kidney, along with multiple soft tissue masses, in the left renal hilum. Considering recurrence or metastasis, the patient was recommended to undergo surgical treatment, but the patient refused. Four months later, CT was re-examined. The tumor had rapidly progressed but the patient refused treatment again. As per the author’s press release (eleven months after the first discovery), the patient is still alive. Conclusion CDC is a rare malignant renal carcinoma, with a high chance of rapid progress, regional lymph nodes involvement and metastasis. It presents diagnostic challenges to clinicians and pathologists, particularly, in the absence of radiographically detectable intrarenal lesions. Definite diagnosis is based on pathological examination combined with immunohistochemical staining.

show abstract

Urologic Pathology

Cited by 3 publications

References 34 publications

Collecting duct carcinoma with retroperitoneal mass as initial presentation: A rare case report

Collecting duct carcinoma with retroperitoneal mass as initial presentation: A rare case report

“Collecting duct carcinoma of the kidney: diagnosis and implications for management”

Collecting duct carcinoma with retroperitoneal mass as initial presentation: a rare case report

Contact Info

Product

Resources

About