Urolithiasis in infants

Jallouli, Mohamed; Mhiri, Riadh; Nouri, Abdellatif

doi:10.1007/s00383-007-1889-7

Cited by 17 publications

(9 citation statements)

References 35 publications

(42 reference statements)

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“…Although UTI is highly prevalent in urolithiasis, as in our study 24% of children with urolithiasis had UTI, the relationship between UTI and urolithiasis is not always evident. The main question is whether the UTI is the cause or the consequence of urolithiasis [31]. In many western countries, urinary calculi is often secondary to identifiable causes in which infection seems to be an important one, whereas in counties where pediatric urolithiasis is considered to be endemic, the etiology remains idiopathic in most cases, and UTI in these countries is believed to be secondary to the urolithiasis [32].…”

Section: Discussionmentioning

confidence: 99%

A Comparison between Clinical and Metabolic Features of Renal Calyceal Microlithiasis and Overt Urolithiasis in Different Pediatric Age Groups

Fahimi¹,

Zoham²,

Sheikh³

et al. 2015

Urol Int

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Introduction: This study assesses the differences in the presentations, complications and metabolic abnormalities of children with renal calyceal microlithiasis (RCM) and overt urolithiasis in different pediatric ages. Materials and Methods: A total of 465 children with urolithiasis were investigated retrospectively. Patients were categorized based on their ages to infancy, early childhood, middle childhood and adolescence. When the hyperechogenic spots on ultrasound imaging were <3 mm, they were considered RCM, and if they were ≥3 mm, they were considered overt urolithiasis. Results: Metabolic abnormalities were detected in 71%; hyperuricosuria in infants, hyperoxaluria in younger children and hypocitraturia in older children were the most common metabolic abnormalities. Hypercalciuria was the only metabolic abnormality that was significantly associated with overt urolithiasis in all pediatric ages (OR 2.25, 95% CI 1.21-4.19). The clinical presentations were not significantly different between RCM and overt urolithiasis; however, complications such as urinary tract infection was significantly higher with overt urolithiasis in infancy (p = 0.01), early childhood (p = 0.02), middle childhood (p = 0.007) and adolescence (p = 0.01). Also, growth retardation was significantly higher with overt urolithiasis in infancy and early childhood (p = 0.02). Conclusions: Most children with urolithiasis have underlying urinary metabolic abnormalities that differ according to the child's age. Despite these differences, hypercalciuria is significantly associated with overt urolithiasis in all pediatric ages. Clinical and laboratory features cannot differentiate RCM and overt urolithiasis; however, complications are significantly higher with overt urolithiasis.

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Section: Discussionmentioning

confidence: 99%

A Comparison between Clinical and Metabolic Features of Renal Calyceal Microlithiasis and Overt Urolithiasis in Different Pediatric Age Groups

Fahimi¹,

Zoham²,

Sheikh³

et al. 2015

Urol Int

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“…The role and efficacy of SWL in infants has been reported in literature by Shukla et al 15. SWL is the preferred management option in infants except in cysteine and uric acid calculi, nephrocalcinosis, malrotated kidney and associated bladder calculi 5. We managed this patient with SWL and the stone was successfully fragmented and the young kid recovered well.…”

Section: Discussionmentioning

confidence: 74%

“…Urolithiasis in children is associated with an identifiable metabolic abnormality in approximately 40%–50% of cases 4. Stone disease in newborns is rarely reported and such cases pose a real challenge in diagnosis as well as management 5. We report a rare case of renal stone disease in a newborn aged 3 days.…”

Section: Introductionmentioning

confidence: 93%

Nephrolithisis in a newborn: a rare case and review of literature

Singh¹,

Sokhal

Sankhwar

et al. 2017

BMJ Case Reports

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Nephrolithiasis, although a common entity in adults, is less common in children and rare in newborns. The evaluation and management strategies of renal stones in neonates are unclear. We report a rare scenario of renal calculus in a newborn aged 3 days presenting with decreased urine output, fever and crying during micturition. Patient was thoroughly investigated and managed conservatively. Further follow-up showed increase in stone size with recurrent urinary tract infections, hence shock wave lithotripsy was performed to successfully break and clear the stone fragments. Patient recovered well and was doing fine until last follow-up.

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“…Przypadki tej choroby u najmłodszych dzieci (do 2 r.ż.) dotyczą obecnie ok. 20% pediatrycznej populacji "kamiczej" [11]. Dodatni "kamiczy" wywiad rodzinny stwierdza się u około 30% dzieci z kamicą nerkową.…”

Section: W St ę Punclassified

Nephrolithiasis in children hospitalized in clinic of nephrology – single center experience

Adamczyk¹,

Bjanid²,

Roszkowska-Bjanid³

et al. 2017

Ann. Acad. Med. Siles.

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W S T Ę P:Aktualnie nie posiadamy wiarygodnych danych dotyczących epidemiologii kamicy układu moczowego w populacji dzieci i młodzieży w Polsce. Wydaje się, że staje się ona chorobą cywilizacyjną i jest coraz częściej rozpoznawana w populacji pediatrycznej. Przyczyn tego zjawiska doszukuje się w zmieniających się nawykach żywie-niowych, braku aktywności fizycznej, epidemii otyłości a nawet globalnym ociepleniu klimatu. M A T E R I A Ł I M E T O D Y:Artykuł przedstawia wyniki retrospektywnej analizy grupy dzieci hospitalizowanych z powodu kamicy układu moczowego oraz metabolicznej predyspozycji do tworzenia się złogów w układzie moczowym, przeprowadzonej w latach 2010-2013 na Oddziale Nefrologii Dzieci Samodzielnego Publicznego Szpitala Klinicznego nr 1 w Zabrzu. Oceny dokonano pod kątem częstości występowania poszczególnych metabolicznych czynników ryzyka oraz ich związku z obrazem ultrasonograficznym. W Y N I K I I W N I O S K I:Grupa dzieci z podejrzeniem kamicy dróg moczowych lub stanu metabolicznej predyspozycji do rozwoju kamicy charakteryzuje się dużą różnorodnością zaburzeń biochemicznych sprzyjających krystalizacji złogów w drogach moczowych. Zaskakujące jest spostrzeżenie o braku powiązań pomiędzy nasileniem zmian o charakterze kamicy w badaniu ultrasonograficznym a zaburzeniami biochemicznymi potencjalnie predysponującymi do tworzenia się złogów. Obraz wapnicy nerek w badaniu ultrasonograficznym wykazuje natomiast wyraźny związek z hiperkalciurią. Pierwotne zaburzenie funkcji przytarczyc oraz przedawkowanie witaminy D rzadko stanowią wyjaśnienie przyczyny kamicy układu moczowego. S Ł O W A K L U C Z O W Ekamica układu moczowego, dzieci, hiperkalciuria, nefrokalcynoza

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Urolithiasis in infants

Cited by 17 publications

References 35 publications

A Comparison between Clinical and Metabolic Features of Renal Calyceal Microlithiasis and Overt Urolithiasis in Different Pediatric Age Groups

A Comparison between Clinical and Metabolic Features of Renal Calyceal Microlithiasis and Overt Urolithiasis in Different Pediatric Age Groups

Nephrolithisis in a newborn: a rare case and review of literature

Nephrolithiasis in children hospitalized in clinic of nephrology – single center experience

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