“…Before the BTX-A injections and 6 weeks after, patients were asked to keep a diary on incontinence, diuresis, CIC timing and the amount of anticholinergic medication during tapering. The urodynamic evaluation was performed at the outset and during the follow-up(6, 12 and 36 weeks) examinations, and variables were defined according to standards recommended by the International Continence Society(ICS) [10]. During the urodynamic assessments, special attention was given to the following key parameters: (1) the reflex volume (RV), which was defined as the infused volume at the start of the first reflex detrusor contraction during the filling phase, (2) the maximum detrusor pressure during voiding (MVP), (3) the bladder compliance, which was defined as the relationship between the change in bladder volume and the change in detrusor pressure (calculated by dividing the volume change by the change in detrusor pressure during the change in bladder volume) and (4) the maximum cystometric capacity (MCC), which was defined as the infused volume during involuntary voiding or the volume at the time that the investigator decided to stop filling (usually at 500 ml).…”