“…The other trial in 50 consecutive men with bladder stones due to various underlying diseases, including BPE, showed in P/F studies BPO in 51%, detrusor underactivity in 10%, and detrusor overactivity in 68% of patients 34. Both trials indicate a possible association between bladder stone formation and BOO/BPO; however, detrusor underactivity or overactivity,34 or other types of BOO, such as urethral stricture, neurogenic bladder dysfunction, or prostate cancer,31 may also play a role. Data suggest that calculi remain lying in the bladder due to incomplete bladder emptying; therefore, any patient with PVR is at risk of developing bladder stones.…”