Urodynamic changes and response rates in patients treated with permanent electrodes compared to conventional wire electrodes in the peripheral nerve evaluation test

Abstract

The results of this study show that application of permanent quadripolar electrodes during PNE prior to chronic neuromodulator implantation leads to significantly higher responder rates and enables more efficient patient selection.

Sacral neuromodulation in urological indications: The Finnish experience

“…This conflicts with another report, in which there were more successful tests after tined lead device implantation compared with PNE [7]. This may be explained by the different patient populations and indications, and by the limited use of the tined lead device in the present study.…”

“…It seems to be effective especially in overactive bladder syndrome and non-obstructive urinary retention [2], but improvement in the symptoms of painful bladder/interstitial cystitis and sexual dysfunction may also be noted during sacral neuromodulation [3]. Advances in technical issues have facilitated the use of the same electrode during the test phase and implantation of the generator (staged implant procedure) [4,5], and may improve the results [6,7]. With tined lead electrodes, an extended trial period, even lasting for 2 weeks, is possible, and is a safe alternative before implantation of the neuromodulator [8].…”

Update on neuromodulation for frequency, urgency, retention, and neurogenic voiding dysfunction

“…This minimally invasive technique of the permanent lead placement has helped to popularize two-stage screening of SNM. Patients screened using the two-stage technique appear to have signifi cantly higher response rates compared with those screened only by PNE, with excellent long-term effi cacy for those undergoing permanent implantation [20][21][22].…”

An update on sacral neuromodulation: where do we stand with this in the management of lower urinary tract dysfunction in 2010?

“…151 mL vs 70 mL)' . Bannowsky et al [64] reported that during PNE with a wire electrode or with a permanent electrode in patients with DO, the bladder capacity increased by 30% and 52%, respectively. The presence or absence of DO did not seem to predict the outcome of preimplant test-stimulation [31].…”

“…[64] reported that during PNE with a wire electrode or with a permanent electrode, the bladder maximum detrusor pressure increased by 68% and 94%, respectively. Everaert et al .…”